Abstract The isocortex of all mammals studied to date shows a progressive increase in the amount and continuity background activity during early development. In humans transition from discontinuous (mostly silent, intermittently bursting) cortex one that is continuously active complete soon after birth critical prognostic indicator. visual rodents this switch continuous occurs 2 d before eye-op...

We have reinvestigated an important issue in the amphibian immunology that has not been settled for years since the pioneer work of Triplett, concerning the necessity of being exposed to organ-specific antigens early in development. It was found that syngeneic Lenses were rejected by frogs, Xenopus laevis, that had been enucleated (eye removed) during early larval life. This rejection did not o...