introduction: while human endothelial progenitor cells (epcs) have been a subject of somehow extensive investigation, epcs from adult mouse hematopoietic system were poorly studied. present investigation is focused on fvb mouse endothelial progenitor cells in terms of their isolation, purification, and expansion. materials and methods: mononuclear cells collected from murine peripheral blood we...

introduction: some studies have demonstrated the potential of herbal drugs for the treatment of various diseases associated with impaired vascular nitric oxide (no). for diagnosis of the mechanism of these herbal plants, it seems necessary to evaluate the herbal extracts on the endothelium cell. the aim of the study was to investigate the effect of extract of trigonella foenum-graecum (t.foenum...

kcnk2 was previously shown to regulate immune-cell trafficking into the central nervous system (cns). kcnk2-/- mice demonstrated a more severe disease course in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis, due to an increased immune-cell migration into the cns. an upregulation of the cellular adhesion molecules icam1 and vcam1 on brain endothelial cells in k...

introduction: endothelial cells are subjected to mechanical forces caused by pulsatile flow and pressure leading to hemodynamic shear stress and circumferential stress on endothelial layer. the study aimed at a quantitative evaluation of endothelial cell morphology by application of cyclic loading. endothelial cells respond to applied loads with adaptation and remodeling. such mechanisms are ma...

Objective(s): The purpose of this study was to detect the protective effects of adiponectin on coagulation dysfunction and its mechanism in sepsis of rats.Materials and Methods: The experimental samples were composed of sham group,   model group that was underwent cecal ligation and puncture (CLP) and three adiponectin treatment groups that treated by adiponectin with different dose (72 μg/kg, ...

purpose: to evaluate the effect of vacuum and flow rate on endothelial cell loss after high versus low vacuum phacoemulsification. methods: this randomized clinical trial was performed on 60 eyes of 60 patients with moderate lens opacity (nuclear sclerosis 3+). all surgeries were performed by one experienced surgeon using stop and chop technique with sovereign white star machine (amo). patients...

Trophoblast stem cells develop from polar trophoectoderm and give rise to the cells that generate the placenta. Trophoblast cells are responsible for the uterinal invasion and vascular remodeling during the implantation of the embryo. However this knowledge is not yet to be confirmed for trophoblast progenitor cells (TPCs). In this study, we aimed to demonstrate that human TPCs (hTPCs) express ...

Introduction: Endothelial progenitor colony forming unit-endothelial cells (CFU-EC) were first believed to be the progenitors of endothelial cells, named endothelial progenitor cells. Further studies revealed that they are monocytes regulating vasculogenesis. The main hindrance of these cells for therapeutic purposes is their low frequency and limited replicative potentials. This study was unde...