Purpose. To evaluate the clinical features, microbiological spectrum, and treatment outcomes of endogenous endophthalmitis. Methods. Retrospective review of consecutive cases with infective endogenous endophthalmitis presenting from 2000 to 2007. The main outcome measure was the visual outcome at the latest follow-up visit. Other outcome measures included microbiological investigations, anatomi...

BACKGROUND To investigate clinical features of infectious endophthalmitis over five years in a South Korean population. METHODS Medical records of consecutive patients diagnosed with infectious endophthalmitis at eight institutions located in Gyeongsangnam-do and Pusan city between January 1, 2004 and July 31, 2010 were reviewed. RESULTS A total of 197 patients were diagnosed and treated. A...

Endophthalmitis is an infection of the anterior and posterior segments of the eye resulting from the introduction of microorganisms following a surgical procedure (postoperative), traumatic penetrating injury (posttraumatic), or metastasis from an infection of a distant site in the body (endogenous). Endophthalmitis can develop into panophthalmitis if the infectious agent invades the cornea and...

We appreciate the comments by Hui et al. (3) concerning our article (1). We agree about the potential benefits of repeated intravitreal injections of antibiotics. Intravitreal antibiotics have become part of the standard treatment for endophthalmitis. The current antibiotic treatment for acute-onset bacterial endophthalmitis includes vancomycin for gram-positive coverage and either ceftazidime ...

BACKGROUND To compare the related factors or manifestations of the two most common isolates of post-operative endophthalmitis, which were Enterococcus spp. and coagulase-negative staphylococci (CNS) in South Korea. METHODS Medical records were reviewed for cases of post-operative endophthalmitis caused by Enterococcus spp. and CNS at eight institutions between January 2004 and July 2010. Vari...

Endophthalmitis is an uncommon diagnosis but can have devastating visual outcomes. Endophthalmitis may be endogenous or exogenous. Exogenous endophthalmitis is caused by introduction of pathogens through mechanisms such as ocular surgery, open-globe trauma, and intravitreal injections. Endogenous endophthalmitis occurs as a result of hematogenous spread of bacteria or fungi into the eye. These ...

PURPOSE To report on endophthalmitis occurrence and associated risk factors following the intravitreal injection of anti-VEGF agents based on a review of published literature. MATERIALS AND METHODS A Medline search was performed using the terms "bevacizumab" and "ranibizumab". A total of 534 English-language articles of varying design and published from 2006 to November 2013 were analyzed for...

Members of the genus Enterobacter are commensal organisms of the gastrointestinal tract and are considered pathogenic only for patients with lowered resistance to infection (e.g., chronic infection, cancer, or diabetes mellitus) or those with impaired immunity (congenital, acquired, or impaired immunity secondary to therapy). We report on four cases of endophthalmitis caused by Enterobacter clo...

PURPOSE The purpose of this study is to identify the possible factors for preserving the eyes after late or suboptimally treated endogenous endophthalmitis secondary to Klebsiella pneumoniae (KP) liver abscess. METHODS A retrospective chart review was conducted for patients admitted with KP liver abscess from January 1991 to June 2012. RESULTS Six hundred and ninety-three patients with KP l...

Candida endophthalmitis represents the most serious ocular complication of candidemia. The pharmacokinetics and pharmacodynamics of fluconazole, amphotericin B, and flucytosine are fairly well established in endophthalmitis therapy. There remains a paucity of clinical data regarding the utility of new antimycotic agents in the treatment of fungal chorioretinitis and endophthalmitis. We report a...