objective: to evaluate effects ofg-csf on a cancelled art cycle due to thin endometrium. materials and methods: in a nonrandomized clinical trial from january 2011 to january 2013 in two tertiary university based hospitals fifteen patients undergoing embryo transfer and with the history of cycle cancellation due to thin endometrium were studied. intrauterine infusion of g-csf was done on the da...

Maternal vitamin intake during pregnancy is crucial for pregnancy outcomes and the child's subsequent health. However, there are few valid instruments for assessing vitamin intake that address the effects of nausea and vomiting during pregnancy (NVP). This study aimed to investigate the validity of a FFQ concerning vitamin intake during early and late pregnancy with and without NVP. The partici...

Background: Pregnancy involves a continuum of complex biological processes. Each of them can be affected by the environment surrounding the pregnant female (e. g. chemicals, nutrition, stress, infection) and data have focused on gametes quality, early blastocyst development and placental function and their perturbations by environmental insults or embryo biotechnologies. During the pregnancy pe...

Background The endometrial echopattern on the day of human chorionic gonadotropin (HCG) administration and its relationship to the outcome of pregnancy after assisted reproductive treatment (ART) cycles was analyzed, prospectively. MaterialsAndMethods This study conducted between 2013 to 2014. The endometrial pattern was evaluated prospectively on the day of administration of HCG in 280 ART cyc...

The purpose of the review is to briefly list widely used 43 drugs that can be as readily available non-toxic radioprotectors and radiomitigators in GDR relevant situations. Caffeine, acetylcysteine, ceruloplasmin, ibuprofen, acetylsalicylic acid, carnosine, cyclosporine, metformin, cholecalciferol, amifostine, artemisinin, theaflavin, succinic chlorophyllin, diltiazem, ferulic glutathione, glyc...

Pentoxifylline, an inhibitor of cAMP phosphodiesterase activity, favours intracellular cAMP concentration increase. In-vitro treatment of semen with pentoxifylline leads to marked augmentation of sperm motility, enhancement of acrosome reaction, increase of sperm penetration into zona-free hamster oocytes, and protection of the sperm plasma membrane. Such properties indicate that the drug may b...

the purpose of this study was to investigate and compare whether the explant supernatants prepared from endometrial tissues during the proliferative phase, secretory phase and early pregnancy differ in immunosuppressive activity. specimens of nonpregnant endometrium from hysterectomies and normal first trimester decidua following elective aspiration termination of pregnancy were obtained. super...

OBJECTIVES The combination of mifepristone and misoprostol is an established method for termination of pregnancy. However, there is no general agreement about how best to evaluate the treatment outcome. STUDY DESIGN In 217 women with an unwanted pregnancy below 49 days of amenorrhoea, ultrasound examination and serum hCG test were performed before treatment and at follow-up. RESULTS Treatme...

Objective: To observe the effect of vitamin C and E administration on endometrial thickness and vascularity in clomiphene citrate stimulated endometrium Method: Research design was randomized clinical trial. Both groups were stimulated with clomiphene citrate. Treatment group was given vitamin C and E, while control group was given placebo. Transvaginal ultrasound examination is used to assess ...

Background: Animal and in vitro studies have shown that 25-OH vitamin D plays a significant role in different parts of body. Few data exist about the role of 25- OH vitamin D in reproduction. Insufficient levels during pregnancy are potentially associated with increased risk of preeclampsia, insulin resistance and gestational diabetes mellitus. Recently, few studies have assessed the prognostic...