to finding out the genetic structure of iranian native horses, as animal blood samples were obtained from diverse areas of iran, in addition, 114 sequences of equine d-loop region were obtained from genbank. total dna of the samples were extracted through salting out procedure and utilized as template for amplification and sequencing of the d-loop region of mtdna. sequence analysis of the 247-b...

Kimura disease is a rare idiopathic chronic inflammatory disorder. It typically presents in the head and neck area, whereas bilateral involvement is unusual. Its diagnosis requires it to be differentiated from other inflammatory diseases and from head and neck tumors. Treatment methods include conservative management, steroid administration, radiotherapy, and surgery; however, no single treatme...

In this note we cast parametrization of certain type of covariance extension problems in polynomial model. We show that the Kimura form of state space realization for maximum entropy solution to Carathéodory’s extension problem is Riccati balanced parametrization. As an application we provide a heuristic algorithm for finding solutions to minimum-phase spectral factor with poles and zeros, give...

The second thiamine-decomposing bacterium, discovered by Kimura et al. (1, 2) was named by the Vitamin B Research Committee Bacillus aneurino lyticus Kimura et Aoyama (BKA) (3). By studying the properties of the enzyme produced by this bacillus, it was found that the action mechanism of the enzyme is completely different from that of Bacillus thiaminolyticus Matsukawa et Misawa (BMM), shell-fis...

Takeshi Kimura, MD; Takeshi Morimoto, MD; Masahiro Natsuaki, MD; Hiroki Shiomi, MD; Keiichi Igarashi, MD; Kazushige Kadota, MD; Kengo Tanabe, MD; Yoshihiro Morino, MD; Takashi Akasaka, MD; Yoshiki Takatsu, MD; Hideo Nishikawa, MD; Yoshito Yamamoto, MD; Yoshihisa Nakagawa, MD; Yasuhiko Hayashi, MD; Masashi Iwabuchi, MD; Hisashi Umeda, MD; Kazuya Kawai, MD; Hisayuki Okada, MD; Kazuo Kimura, MD; C...

A model which is a mixture of the model of infinite alleles and the Ohta-Kimura model of stepwise mutation has been proposed for the study of eletcrophoretic variants in natural populations. Mutations which alter the mobility of a protein are divided into two classes: stepwise mutations and nonstepwise mutations. It is assumed that stepwise mutations follow the Ohta-Kimura model while nonstepwi...

In this note, we characterize the embeddability of generic Kimura 3ST Markov matrices in terms of their eigenvalues. As a consequence, we are able to compute the volume of such matrices relative to the volume of all Markov matrices within the model. We also provide examples showing that, in general, mutation rates are not identifiable from substitution probabilities. These examples also illustr...