نتایج جستجو برای: emp2
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An efficient procedure is introduced to obtain the basis-set limit in electronic structure calculations of large molecular and ionic clusters. This approach is based on a Boys-Bernardi-style counterpoise correction for clusters containing arbitrarily many monomer units, which is rendered computationally feasible by means of a truncated many-body expansion. This affords a tractable way to apply ...
Single-cell RNA sequencing (scRNA-seq) has advanced our understanding of skin biology, but its utility is restricted by the requirement fresh samples, inadequate dissociation-induced cell loss or death, and activation during tissue digestion. Here, we profiled cells using single-nucleus (snRNA-seq) in parallel with scRNA-seq. We found that snRNA-seq identified more spatially functionally releva...
IMPORTANCE The search for novel Alzheimer disease (AD) genes or pathologic mutations within known AD loci is ongoing. The development of array technologies has helped to identify rare recessive mutations among long runs of homozygosity (ROHs), in which both parental alleles are identical. Caribbean Hispanics are known to have an elevated risk for AD and tend to have large families with evidence...
We consider a database machine consisting of n nodes connected by an O(n*processing speed) bandwidth network. Each node consists of a processor, a random access memory, and a slower but much larger memory such as a disk. In order to approach optimal (O(n)) speedup on this hardware architecture, we partition relations roughly evenly among the processors. We study the problem of optimizing multi-...
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