We have identified a gene encoding a new member of the Caenorhabditis elegans GATA transcription factor family, elt-3. The predicted ELT-3 polypeptide contains a single GATA-type zinc finger (C-X2-C-X17-C-X2-C) along with a conserved adjacent basic region. elt-3 mRNA is present in all stages of C. elegans development but is most abundant in embryos. Reporter gene analysis and antibody staining ...

We describe the elt-4 gene from the nematode Caenorhabditis elegans. elt-4 is predicted to encode a very small (72 residues, 8.1 kD) GATA-type zinc finger transcription factor. The elt-4 gene is located approximately 5 kb upstream of the C. elegans elt-2 gene, which also encodes a GATA-type transcription factor; the zinc finger DNA-binding domains are highly conserved (24/25 residues) between t...

The Caenorhabditis elegans GATA transcription factor elt-1 has previously been shown to have a central role in the specification of hypodermal (epidermal) cell fates and acts several cell divisions before the birth of hypodermal cells. Here we report that elt-1 also has essential functions during subsequent development. Reporter gene studies show that elt-1 expression is maintained in lateral s...

language and culture are now deemed to be co-constitutive; hence english language teaching (elt) textbooks should incorporate cultural aspects and promote intercultural competence. however, careful decisions should be made as regards to the cultural content of materials and the ways in which culture is represented. this study was an attempt to deconstruct the patterns of cultural representation...

among the linguistic resources for creating grammatical metaphor, nominalization rewords   processes and properties metaphorically as nouns within the experiential metafunction of language. following halliday's (1998a) classification of grammatical metaphor, the current study investigated nominalization exploited in an english applied linguistics textbook and its corresponding persian translati...

Eltrombopag (ELT) is a novel thrombopoietin receptor agonist for the treatment of idiopathic thrombocytopenic purpura. Previous reports indicate that ELT is mainly eliminated in the liver, although its pharmacokinetic profile has not yet been clarified in detail. The purpose of the present study is to investigate the overall elimination mechanism of ELT. After intravenous administration of ELT ...

Self-assessment and peer-assessment have been appraised in a large number of studies, aiming at investigating their effectiveness in different contexts. However, the challenges of implementing self-assessment and peer-assessment have been investigated rather sporadically. Given that, the purpose of this study was to explore the challenges and probable solutions of implementing self-assessment a...

ELT-2 is the major regulator of genes involved in differentiation, maintenance and function of C. elegans intestine from the early embryo to mature adult. elt-2 responds to overexpression of the GATA transcription factors END-1 and END-3, which specify the intestine, as well as to overexpression of the two GATA factors that are normally involved in intestinal differentiation, ELT-7 and ELT-2 it...

Abstract In addressing the widening research–practice gap in field of second language (L2) education, an increasing emphasis has been placed on a bidirectional and mutually beneficial relationship between L2 researchers practitioners. Through lens ecosystems model, this qualitative study explored how seven at research center China, who collaborated with practitioners other stakeholders developi...