Personalized cardiac electrophysiology simulations have demonstrated great potential to study arrhythmias and help in therapy planning of radio-frequency ablation. Its application analyze vulnerability ventricular tachycardia sudden death infarcted patients has been recently explored. However, the detailed multi-scale biophysical used these studies are very demanding terms memory computational ...

A reduced-order model based on proper orthogonal decomposition (POD) is proposed for the bidomain equations of cardiac electrophysiology. Its accuracy is assessed through electrocardiograms in various configurations, including myocardium infarctions and long-time simulations. We show in particular that a restitution curve can efficiently be approximated by this approach. The reduced-order model...

introduction: treatment of supraventricular arrhythmia includes wide range of medical interventions. herbal remedies are suitable alternatives for synthetic drugs due to their availability, minimal side effects and lower price. pharmacological studies and traditional medical literature point to the cardiovascular effects of the artemisia absinthium l. from compositae family of plants. methods: ...

background and aims: charcot marie tooth disease (cmt) is the most prevalent hereditary neuropathy and its frequency is 1 in 2500. cmt is a heterogeneous disease and has different clinical symptoms. the prevalence of cmt and involved genes differ in different countries. cmt patients experience considerable sleep problems and a higher risk of decreased quality of life. in this work it was aimed ...

Cardiac electrophysiological dysfunction is a major cause of death in humans. Accordingly, electrophysiological testing is routinely performed in intact, conscious, humans to evaluate arrhythmias and disorders of cardiac conduction. However, to date, in vivo electrophysiological studies in mice are limited to anesthetized open-chest or closed-chest preparations. However, cardiac electrophysiolo...