A full-length cDNA encoding chicken tumor necrosis factor superfamily 15 (TNFSF15) was isolated and its functional role was investigated. TNFSF15 transcripts were primarily expressed in spleen, liver, intestinal intraepithelial lymphocytes (IEL), peripheral blood lymphocytes and bursa. In vitro infection of HTC macrophages with three species of Eimeria sporozoites induced TNFSF15 gene expressio...

Lipid rafts are detergent-resistant, liquid-ordered microdomains in plasma membranes that are enriched in cholesterol and sphingolipids and involved in intracellular signal transduction, membrane trafficking, and molecular sorting. In this study, we investigated the possibility that lipid rafts on Eimeria tenella sporozoites may act as platforms for host cell invasion. Flotillin-1, a resident p...

INTRODUCTION It has long been accepted that the resistance developed by fowls to reinfection with the various species of Eimeria which parasitize them is species specific (Tyzzer, Theiler & Jones, 1932; Johnson, 1938). However, careful examination of data obtained in this laboratory suggested that this might not be true for those species which appear to have similar properties. A preliminary re...

The recent cloning of chicken genes coding for interleukins, chemokines, and other proteins involved in immune regulation and inflammation allowed us to analyze their expression during infection with Eimeria. The expression levels of different genes in jejunal and cecal RNA extracts isolated from uninfected chickens and chickens infected with Eimeria maxima or E. tenella were measured using a p...

The invasion and replication of Eimeria tenella in the chicken intestine is responsible for avian coccidiosis, a disease that has major economic impacts on poultry industries worldwide. E. tenella is transmitted to naïve animals via shed unsporulated oocysts that need contact with air and humidity to form the infectious sporulated oocysts, which contain the first invasive form of the parasite, ...

Eimeria belonging to the phylum apicomplexan protozoa is recognized as the the major parasitic disease of poultry. Caecal coccidioisis caused by Eimeria tenella is a major threat to poultry production. The drugs which can inhibit sporulation process are best choice as preventive measures. Anticoccidial drugs have played a major role in the effective control of avian coccidiosis, but their exten...

In the study, zinc oxide nanoparticles (ZNOPs) at concentrations of 20, 40, and 60 mg/kg were tested for their antimicrobial action against oocysts Eimeria tenella. The E. tenella isolated from feces broilers received veterinary hospital in Diwaniyah Province initially diagnosed by compound optical microscopy. confirmed molecularly polymerase chain reaction targeting ITS1 gene with a molecular ...