نتایج جستجو برای: dyslipidemic

تعداد نتایج: 840  

Journal: :Bioorganic & medicinal chemistry letters 2009
Atul Kumar Ram Awatar Maurya Siddharth Sharma Pervez Ahmad A B Singh Gitika Bhatia Arvind K Srivastava

A series of pyranocoumarin derivatives were synthesized and evaluated in vivo for their anti-hyperglycemic as well as anti-dyslipidemic activities. Compounds 7a, 7c, 8a, 8b, 8c, 8e and 8f have shown promising anti-hyperglycemic activities in sucrose loaded model (SLM) as well as sucrose challenged streptozotocin induced diabetic rat model (STZ). Compounds 8a and 8b were showing 38.0% and 42.0% ...

Journal: :Ek'sperimentuli da klinikuri medic'ina 2023

Pathological uterine bleeding is one of the significant problems in gynecology. Different aspects abnormal are discussed (classification, causal factors, mechanisms, diagnosis, treatment). Medications assessed according their priorities (haemostatic effect; regulation menstrual cycle). Preferences dufaston underlined: a) It doesn’t characterize by undrogenic, glucocorticoidal and mineralocortic...

2009
Margalida Rotger PharmD Cornelia Bayard Patrick Taffé Raquel Martinez Matthias Cavassini Enos Bernasconi Manuel Battegay Bernard Hirschel Hansjakob Furrer Rainer Weber Philip E. Tarr Amalio Telenti

Background: HIV-infected individuals have an increased risk of myocardial infarction. Antiretroviral therapy (ART) is regarded as a major determinant of dyslipidemia in HIV-infected individuals. Previous genetic studies have been limited by the validity of the single nucleotide polymorphisms (SNPs) interrogated and by cross-sectional design. Recent genome-wide association studies (GWAS) have re...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2010
Pirkka-Pekka Laurila Jussi Naukkarinen Kati Kristiansson Samuli Ripatti Tuuli Kauttu Kaisa Silander Veikko Salomaa Markus Perola Pekka J Karhunen Philip J Barter Christian Ehnholm Leena Peltonen

OBJECTIVE USF1 is a ubiquitous transcription factor governing the expression of numerous genes of lipid and glucose metabolism. APOA5 is a well-established candidate gene regulating triglyceride (TG) levels and has been identified as a downstream target of upstream stimulatory factor. No detailed studies about the effect of APOA5 on atherosclerotic lesion formation have been conducted, nor has ...

Journal: :European Journal of Clinical Medicine 2023

Background: The relationship between dyslipidemia and the severity of coronavirus disease 2019 (COVID-19) has extensively been characterized in Western population with a dearth data among Nigerians. Hence, current study evaluated lipid/lipoprotein disorders inherent COVID-19 its Methods: This was retrospective conducted 600 patients RT-PCR-confirmed at Eleme treatment facility Port Harcourt, So...

2015
Grazielle V. B. Huguenin Glaucia M. M. Oliveira Annie S. B. Moreira Tatiana D. Saint’Pierre Rodrigo A. Gonçalves Alessandra R. Pinheiro-Mulder Anderson J. Teodoro Ronir R. Luiz Glorimar Rosa

OBJECTIVES To investigate the effect of partially defatted Granulated Brazil nut (GBN) on biomarkers of oxidative stress and antioxidant status of hypertensive and dyslipidemic patients on nutrition and drug approaches. METHODS Ninety one hypertensive and dyslipidemic subjects of both genders (51.6 % men), mean age 62.1 ± 9.3 years, performed a randomized crossover trial, double-blind, placeb...

2013
Shitalkumar P Zambad Davinder Tuli Anoop Mathur Sameer A Ghalsasi Anita R Chaudhary Shailesh Deshpande Ramesh C Gupta Vijay Chauthaiwale Chaitanya Dutt

BACKGROUND Patients with diabesity have a significantly increased risk of developing cardiovascular disease. Therefore, therapy addressing the multiple metabolic abnormalities linked with diabesity and leading to further reduction of cardiovascular risk is highly desirable. Activation of the TGR5 receptor holds therapeutic potential for diabesity. In the present study, we evaluated the efficacy...

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