The incidence of peptic ulcer perforation was found to be more common in the middle age, male and in nonvegetarians. Smoking, alcohol and NSAIDs use played significant role in peptic ulcer perforation. Perforation was commonest in “O” blood group cases. Degree of peritoneal contamination was a major contributing factor in morbidity and mortality. Mostly cases had anterior wall duodenal perforat...

BACKGROUND Perforation peritonitis is the most common surgical emergency encountered by the surgeons all over the world as well in Pakistan. The spectrum of etiology of perforation peritonitis in tropical countries continues to differ from its western counter part. This study was conducted at Dow University of health sciences and Civil Hospital Karachi (DUHS & CHK) Pakistan, designed to highlig...

Most patients with chronic duodenal ulcer disease have Helicobacter pylori infection and eradicating it considerably reduces the relapse rate. The prevalence of H pylori in 80 patients (mean age = 52 years, range 17-85) presenting with acute perforated duodenal ulcer was examined and compared with age and sex matched hospital control patients. H pylori state was assessed by serum anti-H pylori ...

In the emergency treatment of a perforated duodenal ulcer (DU), after surgical closure of the perforation and treatment of the secondary peritonitis, higly selective vagotomy(HSV) is a valid therapy to prevent recurrence of the underlying disease.

The use of the terms 'acute' and 'chronic' when describing perforated duodenal ulcers has sometimes produced confusion. It is obviously incorrect to speak of an 'acute perforation' because all perforations are acute although some may be small and therefore leak slowly. On the other hand, it is established that both acute and chronic ulcers perforate, although it may appear to be of academic int...

BACKGROUND Spontaneous gastric perforation is a rare clinical disorder. The majority of the available data have been reported in the neonatal age group. There are a few cases of spontaneous gastric perforation in preschool children. To our knowledge, there is no published information on spontaneous gastric perforation in older children and adolescents. CASE REPORT We describe the presentation a...

438 Figure S1A–C). After 3 months, control contrastenhanced computed tomography (CECT) demonstrated complete regression of the WOPN; therefore, the transmural stent was removed. After 1 year of follow-up, no recurrence of collection was detected on CECT. Control gastroduodenoscopy demonstrated a diverticulum of the duodenal bulb (diameter, 3 cm) where the penetrating ulcer had previously been p...

Background.  There is no literature review on gastroduodenal perforation or ulcer (GDPU) with rotavirus (RV) and norovirus (NoV) gastroenteritis. Methods.  Pediatric cases of GDPU or upper gastrointestinal bleeding with RV and NoV gastroenteritis were searched from September 1974 until October 2015 using PubMed, Google for English, other-language-publications, and Ichushi (http://www.jamas.or.j...

Instrumental perforation of the oesophagus is a serious and, unfortunately, not a very rare accident. The occurrence in addition of perforation of a duodenal ulcer constitutes a situation which is rare, difficult to diagnose, and fraught with great danger to the patient. Simultaneous perforation of multiple peptic ulcers has been described in several reports since that of Finney (1900). As pept...