BACKGROUND Recent research has indicated that transitions into and out of daylight saving time (DST) unbalance the physiological circadian rhythm and may lead to sleep disturbance. Sleep deprivation may have negative effects on motivation, attention and alertness and thus it is possible that transitions into and out of DST may increase accident rates. AIMS To explore the impact of DST transit...

Many cancers harbor homozygous DNA deletions (HDs). In contrast to other attributes of cancer cells, their HDs are immutable features that cannot change during tumor progression or therapy. I describe an approach, termed deletion-specific targeting (DST), that employs HDs (not their effects on RNA/protein circuits, but deletions themselves) as the targets of cancer therapy. The DST strategy bri...

The geomagnetic activity of the Dst index is analyzed using wavelet transforms and it is shown that the Dst index possesses properties associated with self-affine fractals. For example, the power spectral density obeys a powerlaw dependence on frequency, and therefore the Dst index can be viewed as a self-affine fractal dynamic process. In fact, the behaviour of the Dst index, with a Hurst expo...

It is now well recognized that pre-transplant donor-specific blood transfusion (DST) has a beneficial effect on the survival of allografts. To determine the optimal interval between DST and transplantation, and to analyze the mechanisms of this effect, the survival of cardiac allografts to rats which received a single DST was examined. The cardiac allograft survival was found to be prolonged wh...

BACKGROUND Resistance to commonly used antituberculosis drugs is emerging worldwide. Conventional drug-susceptibility testing (DST) methods are slow and demanding. Alternative, rapid DST methods would permit the early detection of drug resistance and, in turn, arrest tuberculosis transmission. METHODS A cost-effectiveness analysis of 5 DST methods was performed in the context of a clinical tr...

Investigators continue to debate whether the Dexamethasone Suppression Test (DST) reflects clinical severity or degree of melancholia ("endogeneity"). To evaluate this question, we studied 73 drug-free inpatients diagnosed with Schedule for Affective Disorders and Schizophrenia/Research Diagnostic Criteria (SADS/RDC) as having major depressive disorder (MDD). We compared absolute and dichotomou...

erated interest and excitement in psychological research, as demonstrated by the recent statement, “...the dynamical perspective has emerged as a primary paradigm for the investigation of psychological processes at different levels of personal and social reality” (Vallacher et al., 2010, p. 263). What is less clear to the authors is the degree to which this excitement is justified. Like many ps...

BACKGROUND Even though the WHO-endorsed, non-commercial MODS assay offers rapid, reliable TB liquid culture and phenotypic drug susceptibility testing (DST) at lower cost than any other diagnostic, uptake has been patchy. In part this reflects misperceptions about in-house assay quality assurance, but user convenience of one-stop procurement is also important. A commercial MODS kit was develope...

Three-hourly average values of the Dst, AE and ap geomagnetic activity indices have been studied for 1 year's duration near the solar minimum (1974) and also at the solar maximum (1979). In 1979 seven intense geomagnetic storms (Dst <A100 nT) occurred, whereas in 1974 only three were reported. This study reveals: (1) the yearly average of AE is greater in 1974 than in 1979, whereas the inverse ...

this study investigated the effect of applying the dynamic system theory (dst) and cognitive linguistics (cl) insights into grammar instruction on efl learners’ learning of english prepositions and learner autonomy. sixty iranian efl learners at the lower-intermediate level of language proficiency were randomly assigned to 1 experimental and 1 control group. the 2 groups filled out an autonomy ...