BACKGROUND The design, synthesis, characterization and evaluation of a novel series of non-detergent spermicides has led to the discovery of two unique molecules (DSE-36 and DSE-37) that were approximately 25 times more potent spermicides than nonoxynol-9 (N-9). METHODS Normal human spermatozoa were used to assess the spermicidal activity (Sander-Cramer Assay), the effect on sperm-membrane in...

BACKGROUND Paraoxonase 1 (PON1) is a high- density lipoprotein (HDL)-associated enzyme, displaying esterase and lactonase activity. The PON1 is involved in a variety of inflammatory diseases, metabolizing toxic oxidized lipids and detoxifying of organophosphorus insecticide compounds and nerve agents. OBJECTIVES The aim of this study was to investigate the effects of methanolic date seed extr...

A comparison of published estimates of mycorrhizal and dark septate endophyte (DSE) colonisation from various ecosystems suggests that DSE may be as abundant as mycorrhizal fungi as judged by the proportion of host plants colonised in mixed plant communities, or by the extent of colonisation in sampled root systems. While many strides have been made in understanding the ecological significance ...

INTRODUCTION Previous studies have shown an exercise-induced increase in circulating adhesion molecules (sICAM-1 and sVCAM-1) in patients with coronary artery disease (CAD). The aim of this study was to evaluate the diagnostic role of changes in serum adhesion molecules in the setting of a dobutamine stress echocardiogram (DSE). METHODS Thirty patients (18 men and 12 women aged 63.3 ± 10.67 y...

STUDY OBJECTIVE To determine whether the prognostic value of dobutamine stress echocardiography (DSE) performed early after acute myocardial infarction (AMI) is as high in diabetic patients as in nondiabetic patients. DESIGN Inception cohort study. SETTING Tertiary cardiac referral center. PATIENTS AND INTERVENTIONS Three hundred thirty-eight patients (116 diabetic and 222 nondiabetic) wh...

OBJECTIVES We sought to evaluate the impact of dobutamine stress echocardiography (DSE) in patients with known rheumatic mitral stenosis (MS) in order to assess its safety, feasibility, and prognostic correlation to well-known clinical outcomes. BACKGROUND Noninvasive prognostic assessment of MS still represents an unresolved task in patients with clinically challenging disease. METHODS Dob...

The role of early coronary revascularization in the management of stable coronary artery disease remains controversial. The aim of this study was to evaluate the impact of early coronary revascularization on long-term outcomes (>10 years) after an ischemic dobutamine stress echocardiography (DSE) in patients with known or suspected coronary artery disease. Patients without stress-induced ischem...

Dynamic symbolic execution (DSE) is a well-known technique for automatically generating tests to achieve higher levels of coverage in a program. Two keys ideas of DSE are to: (1) seed symbolic execution by executing a program on an initial input; (2) using concrete values from the program execution in place of symbolic expressions whenever symbolic reasoning is hard or not desired. We describe ...

Discordance between the (123)I-labelled 15-iodophenyl-3-R, S-methyl pentadecanoic acid (BMIPP) and (201)Tl findings may indicate myocardial viability (MV). This study compared dobutamine stress echocardiography (DSE) and single-photon emission computed tomography (SPECT) using the dual tracers for assessment of MV and prediction of functional recovery after acute myocardial infarction (AMI). DS...

BACKGROUND The increasing role of percutaneous coronary interventions (PCI) in the treatment of coronary artery disease and relatively high restenosis rate following PCI require the introduction of available, easy to perform and cost-effective tests that would enable detection of restenosis after PTCA and identification of patients at particularly high risk of restenosis. AIM To estimate the ...