background blood transfusion is one of the many ways, through which toxoplasma gondii (t. gondii), a protozoan parasite, can be transmitted to humans. objectives this cross sectional study aimed to evaluate the seroprevalence of toxoplasma infection and related epidemiological features among healthy blood donors. materials and methods a total of 375 blood samples from donors were tested for spe...

The aim is to estimate the influence of sinusoidal (ac) field in combination with the cytostatic drug gemcitabine on the therapeutic effect of malignant cells. Electrotreatment is cell line dependent. There is threshold frequency window (1Hz) that is the most suitable for drug delivery. Hematopoietic cells are more sensitive to the electrotreatment as compared with human lymphocytes from health...

background: this study aimed at determining the prevalence and associated risk factors for asymptomatic malaria parasitaemia and anemia among blood donors in a private medical laboratory in benin city, nigeria. methods: venous blood was collected from a total of 247 blood donors. malaria status, abo, rhesus blood groups and hemoglobin concentration of all participants were determined using stan...

We report that simple glycoside donors can drastically shift the equilibria of glycosyltransferase-catalyzed reactions, transforming NDP-sugar formation from an endothermic to an exothermic process. To demonstrate the utility of this thermodynamic adaptability, we highlight the glycosyltransferase-catalyzed synthesis of 22 sugar nucleotides from simple aromatic sugar donors, as well as the corr...

Hospital-based studies suggest that hepatitis C virus (HCV) infection causes frequent cirrhosis, hepatocellular carcinoma, and mortality, but epidemiologic studies have shown less morbidity and mortality. The authors performed a retrospective cohort study of 10,259 recombinant immunoblot assay-confirmed, HCV antibody-positive (HCV+), allogeneic blood donors from 1991 to 2002 and 10,259 HCV anti...

Although filtration leukapheresis (FL) is a relatively simple and efficient means of harvesting neutrophils (PMN) for transfusion, the PMN obtained by this procedure have both functional and morphologic abnormalities induced when the cells adhere to nylon wool filters used in FL. Adherence to nylon wool causes a partial degranulation of PMN together with the production of superoxide at cell sur...

BACKGROUND The number of patients awaiting allograft transplantation in the UK exceeds the number of organs offered for transplantation each year. Most organ donors tend to be young, fit and healthy individuals who die because of trauma or sudden cardiac arrest. Patients who die from drug and poison intoxication tend to have similar characteristics but are less frequently offered as potential o...