When one drug influences the level or activity of another drug this is known as a drug-drug interaction (DDI). Knowledge of such interactions is crucial for patient safety. However, the volume and content of published biomedical literature on drug interactions is expanding rapidly, making it increasingly difficult for DDIs database curators to detect and collate DDIs information manually. In th...

BACKGROUND Sensation-seeking among prisoners with substance dependence difficulties (drug and/or alcohol) was examined. This topic is under-researched in a prisoner sample. AIMS The aims are to examine the association between sensation-seeking, other personality variables, and substance dependency among prisoners, and to examine if sensation-seeking can be refined. METHODS Adult male prison...

Background: Sensation-seeking among prisoners with substance dependence difficulties (drug and/or alcohol) was examined. This topic is under-researched in a prisoner sample. Aims: To examine the association between sensation-seeking, other personality variables, and substance dependency among prisoners. To examine if sensation-seeking can be refined. Methods: Adult male prisoners (n = 200) comp...

Drug dependency is a highly prevalent mental health disorder that imposes a significant burden on those directly affected, health care systems, and society in general. There is substantial heritability in the susceptibility to drug addiction, which indicates that there are genetic risk factors. Variation in the human genome is abundant and can directly affect drug dependency phenotypes, for exa...

conclusions the present study revealed different degrees of malnutrition among drug addicts with multiple deficiencies in both macro- and micronutrients. results the mean age, body weight, height, and bmi were 34.4 ± 9.7 years, 63.1 ± 10.1 kg, 171.1 ± 11.6 cm, and 21.8 ± 4.4 kg/m², respectively. according to the percentile status of the bmis, the results showed that 35.2%, 20.4%, 37%, and 7.4% ...

Tolerance and dependence are two main problems that have limited morphine administration. There are several reports on the effect of some medicinal plants on morphine-induced tolerance and dependence. In this study we investigated the effect of Ferula persica (FP) extract on modulation of withdrawal syndrome sign (WSS). For this purpose, male Albino mice (25-30 g, n=30) were used. Morphine was ...

Tolerance and dependence are two main problems that have limited morphine administration. There are several reports on the effect of some medicinal plants on morphine-induced tolerance and dependence. In this study we investigated the effect of Ferula persica (FP) extract on modulation of withdrawal syndrome sign (WSS). For this purpose, male Albino mice (25-30 g, n=30) were used. Morphine was ...