Abstract Drug delivery is one of the major issues in the world of science, which receives a large part of the research in various fields. The ultimate goal of drug delivery is to help the patient with developing advanced drug delivery systems. These systems revolutionize the treatment of many diseases including cancer. Effective drug carriers can significantly reduce the undesirable side effec...

Albumin is a multifaceted, highly soluble, stable, non toxic, non poisonous, biocompatible and biodegradable plasma protein. Because of its versatile nature, it can be used for the delivery of the drugs, hormones, metals and fatty acids by binding to its specific binding sites. The structure, location, size, charge and hydrophobicity of these drug binding sites are very important to optimize th...

Drug molecules transformed into nanoparticles or endowed with nanostructures with or without the aid of carrier materials are referred to as "nanomedicines" and can overcome some inherent drawbacks of free drugs, such as poor water solubility, high drug dosage, and short drug half-life in vivo. However, most of the existing nanomedicines possess the drawback of low drug-loading (generally less ...

   The aim of the present study was to develop a single unit, site-specific matrix tablets of aceclofenac allowing targeted drug release in the colon with a microbially degradable polymeric carrier, chondroitin suphate (CS) and to coat the optimized batches with a pH dependent polymeric. The tablets were prepared by wet granulation method using starch mucilage as a binding agent and HPMC K-100 ...

Objective: Intravascular catheter-associated infection has been increasing hospitalization in post-surgery patients mainly due to microbial colonization of the catheter surface and formation of a superficial biofilm layer. The present study is aimed in developing an effective antibacterial device which can prevent colonization of organisms by modification of catheter. Methods: In the present st...

The term “immediate release” pharmaceutical formulation includes any in which the rate of release drug from or absorption drug, is neither appreciably, nor intentionally, retarded by galenic manipulations. These tablets disintegrate rapidly and get dissolved to medicaments. It may be provided for way an appropriate pharmaceutically acceptable diluent carrier, carrier does not prolong, appreciab...