Combinatorial droplet microfluidic devices with programmable microfluidic valves have recently emerged as a viable approach for performing multiplexed experiments in microfluidic droplets. However, the serial operation in these devices restricts their throughput. To address this limitation, we present a parallelized combinatorial droplet device that enhances device throughput via droplet bifurc...

The surface flows on a droplet in an oscillating pressure field are simulated numerically by solving the Navier-Stokes equations using the Arbitrary Lagrangian-Eulerian and level set coupled method. Detailed transient flow fields in and around the droplet are calculated by performing parallel computations, and the flow phenomena in a thin layer around the droplet surface are discussed. The reci...

The PAT family proteins, named after perilipin, adipophilin, and the tail-interacting protein of 47 kDa (TIP47), are implicated in intracellular lipid metabolism. They associate with lipid droplets, but how is completely unclear. From immunofluorescence studies, they are reported to be restricted to the outer membrane monolayer enveloping the lipid droplet and not to enter the core. Recently, w...

A quantitative description of the dynamics of droplet motion has been a long-standing concern in electrowetting research. Although many static and dynamic models focusing on droplet motion induced by electrowetting-on-dielectric (EWOD) already exist, some dynamic features do not fit these models well, especially the dynamic saturation phenomenon. In this paper, a dynamic saturation model of dro...

Accurate and precise nucleic-acid quantification is crucial for clinical and diagnostic decisions, as overestimation or underestimation can lead to misguided treatment of a disease or incorrect labelling of the products. Digital PCR is one of the best tools for absolute nucleic-acid copy-number determination. However, digital PCR needs to be well characterised in terms of accuracy and sources o...

Water droplet impact on surfaces is a ubiquitous phenomenon in nature and industry, where the time of contact between droplet and surface influences the transfer of mass, momentum and energy. To manipulate and reduce the contact time of impacting droplets, previous publications report tailoring of surface microstructures that influence the droplet - surface interface. Here we show that surface ...

The transient response of a millimeter-sized sessile droplet under electrical actuation is experimentally investigated. Under DC actuation, the droplet spreading rate increases as the applied voltage is increased due to the higher electrical forces induced. At sufficiently high DC voltages, competition between the electrical actuation force, droplet inertia, the retarding surface tension force ...

Deformation of a rotating two-lobed liquid droplet was simulated numerically by solving the three-dimensional Navier-Stokes equations using the level set method. The two-lobed droplet was formed by rotating a spherical droplet; the droplet changed its shape from the sphere to the rotating ellipsoid, and to the two-lobed shape. It was found that the time histories of the deformation of two-lobed...

Irregularities in the perimeter of a water droplet adhering to a vertical pane of glass cause perturbations in the curvature of the droplet surface. When laser light passes through such a droplet, the perturbations produce a far field refraction caustic, which is a section of the caustic known as the parabolic umbilic in the catastrophe theory classification. As the water evaporates and the dro...

This project will develop cloud droplet probes and phase-Doppler anemometry for measuring sizesegregated droplet concentrations at high wind speeds in the ABL. The data will be used for investigating droplet dynamics in the marine atmospheric boundary layer, characterizing the droplet surface flux source function, and determining the effect spray drops have on air-water surface exchange process...