Nasopharyngeal carcinoma (NPC) is most commonly an undifferentiated carcinoma with a strong association with the Epstein Barr virus (EBV) and familial tendency. MRI is the modality of choice for NPC staging of the primary tumour and nodal metastases. The primary tumour spreads to the nasal cavity and infrequently to the oropharynx (T1); parapharyngeal space, medial and lateral pterygoid, and pr...

BACKGROUND Preoperative radiotherapy (RT) in combination with fluoropyrimidine-based chemotherapy (CT) is the standard of care in patients with locally advanced, T3-T4 N0-2, rectal cancer (LARC). Given the correlation between RT dose-tumor response and the prognostic role of the tumor regression grade (TRG), treatment intensification represents an area of active investigation. The aim of the st...

OBJECTIVE To investigate the differences between tumor sizes measured by preoperative computed tomography (CT) imaging and pathologic examination of surgical specimens in Chinese patients who received extirpative surgery for renal tumors. METHODS From September 2008 to September 2010, 204 patients with renal tumors treated in the Renji Hospital were enrolled in this study, and their clinicopa...

OBJECTIVE Concurrent chemoradiotherapy is standard of care in stage III non-small-cell lung cancer, although surgery may be beneficial in selected patients in whom induction therapy has achieved 'down-staging' of mediastinal nodal disease. Previous studies incorporated treatment 'splits' for re-evaluation, and such gaps lead to poorer survival in patients undergoing chemoradiotherapy. We descri...

This study aimed to investigate the effect of ANRIL on the lymphangiogenesis and lymphatic metastasis in colorectal cancer. Using RT-PCT and Northern blot, we detected ANRIL expression in tissues (cancer vs. normal) and cell lines (HCoEpic, SW480, HT29, LoVo and HCT116), finding that ANRIL was overexpressed in colorectal cancer. By statistical analysis, increased ANRIL was found to be in close ...

background endometrial carcinoma is a highly prevalent gynecologic malignancy. the international federation of gynecology and obstetrics (figo) staging system underwent significant revision on 2009. key changes in the figo staging system include simplification of stage i endometrial cancer and removal of cervical mucosal invasion as a separate stage. mri is a noninvasive diagnostic method for p...