Down syndrome [DS] is the most common chromosomal disorder in population manifested by intellectual disabilities of varying degrees, often accompanied disorders organ systems. Compared to children without DS, these have a greater risk developing malignancy such as acute leukemia. Leukemia blood cells and lymph nodes form cancer children. Its treatment with DS more complex compared this syndrome...

The gardener picks up a fir cone and rolls it through the quiet room straight towards a small child in the audience. Either the child leaves the fir cone lying where it is, or perhaps picks it up. Perhaps the child will later roll the fir cone on towards another child. Or make a gravel track around its mother. Maybe the child kneels down beside a bed full of branches and twigs and feels the mat...

This paper describes how fertility is determined in a model that assumes the existence of child-care services. When child-care services exist, two multiple states result: a state that brings about low fertility with low female labor participation, and a state that brings about high fertility with high female labor participation. This result is consistent with the positive correlation that is fo...

Parents, genetic counselors, and nurses were shown an 18-minute video-taped discussion involving parents of persons with Down syndrome and were asked to complete an evaluation. Some of the statistically significant differences were as follows: 89% of mothers believed that the film was an accurate portrayal of parental attitudes compared with 14% of the genetic counselors and 40% of the nurses; ...

PURPOSE  To describe leisure participation for school-aged children with Down syndrome and to investigate how factors, classified by the World Health Organisation's International Classification of Functioning, Disability and Health, influence their leisure participation. METHOD  Families in Western Australia with a child aged 5-18 years with Down syndrome were surveyed in a population-based s...

Disorder in re-methylation process of homocysteine to methionine due to mutation in betaine homocysteine methyltransferase enzyme (BHMT) coding gene, leads to decrease in S-adenosyl methionine (SAM) synthesis which takes part in DNA methylation as a methyl donor. As a result, it can promote hypo-methylation of DNA, chromosome instability, and chromosome missegregation, which in turn is one of t...

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We examined the development of neural control processes underlying stance balance in both developmentally normal children and children with Down syndrome to test the hypothesis that motor deficiencies in children with Down syndrome are associated with deficits within the automatic postural control system. We compared children with Down syndrome and developmentally normal children in two age gro...