Background Despite increasing reports of successful pregnancies whilst using Efavirenz (EFZ), the drug remains Category C during pregnancy due to concerns around teratogenicity [1]. Additionally, EFZ can render many hormonal methods of contraception less effective. For these reasons, UK guidance suggests that HIV positive women should be informed of these effects before commencing treatment [2]...

bootstrapping the dea is one of the current methods of measuring robust efficiency by constructing a confidence interval and measuring the noise (bias) in production. in this study, two estimators: the conventional data envelopment analysis (dea) and bootstrap simulation with 2,000 bootstrap iterations were applied on a cross sectional data of 296 broiler farms in peninsular malaysia. the objec...

Among today’s rich economies, per capita output levels diverged before converging to the levels of the frontier economy. Since frontier economies grew at stable rates, non-frontier economies display an S-shaped transition path. Along this transition, there are "catapult effects": longer episodes of stagnation are associated with faster subsequent rates of convergence to the frontier. Many of to...

A recombinant ketoreductase from Pichia glucozyma (KRED1-Pglu) was used for the enantioselective reduction of various mono-substituted acetophenones. Reaction rates of meta- and para-derivatives were consistent with the electronic effects described by σ-Hammett coefficients; on the other hand, enantioselectivity was determined by an opposite orientation of the substrate in the binding pocket. R...

The conventional Cobb-Douglas production function model require strong assumptions such as the constant elasticity and the entire frontier efficiency. The varying elasticity production function is an useful extension but it does not take frontier efficiency into account, and the data envelope analysis model involves the use of linear programming methods to estimate the frontier efficiency where...

We study some structural and topological properties of the frontiers of objects in a certain class of discrete spaces, in the framework of simplicial complexes and partial orders. In a previous work, we introduced the notion of frontier order, which allows to define the frontier of any object in an n-dimensional space. The main goal of this paper is to exhibit the links which exist between fron...

We present a new spatial partitioning scheme called frontier sets. Frontier sets build on the notion of a potentially visible set (PVS) [ARB90, TS91]. In a PVS a world is sub-divided into cells and for each cell all the other cells that can be seen are computed. Frontier sets represents regions of mutual invisibility. One frontier in a frontier set considers pairs of cells, A and B. It lists tw...

We provide an analysis of frontier market equities with respect to world market integration and diversification. Principal component results reveal that frontier markets exhibit low levels of integration. In contrast with developed and emerging markets, frontier markets offer no indication of increasing integration through time. Furthermore, individual frontier market countries do not exhibit c...

In the use of peer group data to assess individual, typical or best practice performance, the effective detection of outliers is critical for achieving useful results, particularly for two-stage analyses. In the DEA-related literature, prior work on this issue has focused on the efficient frontier as a basis for detecting outliers. An iterative approach to deal with the potential for one outlie...