Abstract Non-invasive brain stimulation (NIBS) interventions are promising for the treatment of psychiatry disorders. Notwithstanding, mechanisms action NIBS over dorsolateral prefrontal cortex (DLPFC), a hub that modulates affective and cognitive processes, have not been completely mapped. We aimed to investigate regional cerebral blood flow (rCBF) changes DLPFC interconnected subgenual anteri...

Introduction: Working memory plays a critical role in cognitive processes which are central to our daily life. Neuroimaging studies have shown that one of the most important areas corresponding to the working memory is the dorsolateral prefrontal cortex (DLFPC). This study was aimed to assess whether bilateral modulation of the DLPFC using a noninvasive brain stimulation, namely transcranial di...

Drug-related cues induce craving, which may perpetuate drug use or trigger relapse in addicted individuals. Craving is also under the influence of other factors in daily life, such as drug availability and self-control. Neuroimaging studies using drug cue paradigms have shown frontal lobe involvement in this contextual influence on cue reactivity, but have not clarified how and which frontal ar...

The dorsolateral prefrontal cortex (DLPFC) has been implicated in the ability to perform complex behaviors requiring the implementation of cognitive control. A central supposition of models of prefrontal function is that the DLPFC engages control by selectively modulating the activity of target structures to which it is connected, but no studies in the primate have directly investigated DLPFC o...

Gamma-aminobutyric acid (GABA)ergic and glutamatergic neurotransmissions in the prefrontal cortex decreases with age. Further, cognitive function mediated through the dorsolateral prefrontal cortex (DLPFC) also declines with age. Although neuroimaging studies have demonstrated decreased levels of these substances, direct neurophysiological data investigating the effect of aging in the DLPFC in ...

The lateral prefrontal and orbitofrontal cortices have both been implicated in emotion regulation, but their distinct roles in regulation of negative emotion remain poorly understood. To address this issue we enrolled 58 participants in an fMRI study in which participants were instructed to reappraise both negative and neutral stimuli. This design allowed us to separately study activations refl...

Research to-date has not successfully demonstrated consistent neural distinctions for different types of ambiguity or explored the effect of grammatical class on semantic selection. We conducted a relatedness judgment task using event-related functional magnetic resonance imaging (fMRI) to further explore these topics. Participants judged relatedness within word pairs. Consistent and inconsiste...

Unrealistic optimism is common among people making self-evaluations while reduced optimism has been linked to increased depressive symptoms. Given the importance of optimism for adaptive functioning, surprisingly little is known about resting brain states underlying optimistic and depressive tendencies. In the current study, two resting-state indices were used to examine neural correlates of th...

Many attempts have been made to enhance hypnotizability. The most recent studies adopted the non-invasive brain stimulation deactivate dorsolateral prefrontal cortex (DLPFC) during hypnosis, indicating this as a promising approach. However, it is still no clear whether individual factors can predict effects of on In present study we phenomenological consciousness inventory (PCI) retrospectively...

The aim of the current study was to attempt replicate finding that individual alpha frequency (IAF) as well absolute difference between IAF and 10 Hz stimulation (IAF-prox) is related treatment outcome. Correlations were performed investigate relationship IAF-prox percentage symptom improvement in a sample 153 patients with major depressive disorder treated (N = 59) left dorsolateral prefrontal...