PURPOSE To compare the dosimetric differences between jaw tracking technique (JTT) and static jaw technique (SJT) in dynamic intensity-modulated radiotherapy (d-IMRT) and assess the potential advantages of jaw tracking technique. METHODS Two techniques, jaw tracking and static jaw, were used respectively to develop the d-IMRT plans for 28 cancer patients with various lesion sites: head and ne...

The lack of robust radiobiological data hampers the further optimization emerging 177Lu-PSMA-directed radioligand therapy (RLT). This study aims to explore several conventional parameters in assessment outcomes tumor and normal organs at risk (OARs) for castration-resistant prostate cancer (CRPC) patients. 20 patients received a median 3 (range 1–6, totally 86 cycles) 177Lu-PSMA-617 RLT were re...

PURPOSE The aim of this work was to evaluate the variation of dose in organs at risk (OARs) in fractionated high dose rate intracavitary brachytherapy (HDR-BT) for cervical cancer. MATERIAL AND METHODS A prospective study was carried out on 20 cervical cancer patients treated with fractionated (HDR-BT). International Commission on Radiation Units and Measurement (ICRU) bladder (bICRU) and rec...

The purpose of this study was to determine dose to the planning target volume (PTV) and organs at risk (OARs) from portal imaging (PI) of the craniofacial region in pediatric brain tumor patients treated with intensity-modulated radiation therapy (IMRT). Twenty pediatric brain tumor patients were retrospectively studied. Each received portal imaging of treatment fields and orthogonal setup fiel...

Background: The development of intensity-modulated radiotherapy (IMRT) has revolutionized the management of nasopharyngeal carcinoma (NPC). The purpose of this study was to investigate the impact of clinical stage on radiation doses to organs at risk (OARs) in NPC. Material and Methods: One hundred and forty-eight patients with newly diagnosed and untreated NPC were prospectively enrolled. Base...

Background: Presence of artifacts, caused by dental filling high-Z materials (DFM), on intensity-modulated radiation therapy (IMRT) treatment plan CT images may lead to uncertainty in head and neck calculated dose distributions. Hence, the purpose of this study was to investigate the effects of DFM on the IMRT calculated dose distribution and consequent radiobiological derived outcomes for naso...

PURPOSE To investigate the influence of inhomogeneity corrections on stereotactic treatment plans for non-small cell lung cancer and determine the dose delivered to the PTV and OARs. MATERIALS AND METHODS For 26 patients with stage-I NSCLC treatment plans were optimized with unit density (UD), an equivalent pathlength algorithm (EPL), and a collapsed-cone (CC) algorithm, prescribing 60 Gy to ...

Objective To explore the advantages of dosimetry and treatment efficiency tangent-arc technology in deep inspiration breath-hold radiotherapy for breast cancer. Methods Forty patients with left-sided cancer who were treated our hospital from May 2020 to June 2021 randomly selected divided into two groups. The first group’s plan was a continuous semi-arc that started at 145° ( ± 5°) stopped 325°...

The comparison between intensity-modulated proton therapy (IMPT) and volume-modulated arc (VMAT) plans, based on models of normal tissue complication probabilities (NTCP), can support the choice radiation modality. IMPT irradiation plans for 50 patients with head neck tumours originally treated photon have been robustly optimised against density setup uncertainties. dose distribution has calcul...

Dosimetric comparisons between RapidArc (RA) and conventional Intensity-Modulated Radiation Therapy (IMRT) techniques for nasopharyngeal carcinoma (NPC) were performed to address differences in dose coverage of the target, sparing of organs-at-risk (OARs), delivery of monitor units (MUs) and time, to assess whether the RA technique was more beneficial for treatment of NPC. Eight NPC patients (S...