Introduction: Radiotherapy (RT) plan evaluation using dose response models has become a feasible approach in routine clinical practice. Although there are several tools for this task, they suffer from limitations including number of different dose response models and parameters. In the present study, we aimed to develop a free program for RT plan evaluation based on a variety ...

Background: An effective polymer gel dosimeter can be fabricated by varying the composition of its chemical components. Materials and Methods: The MAGAT gel dosimeter formulations that used different compositions of Methacrylic acid (MAA) and gelatin were extensively investigated in the present study according to the R2–dose response and R2–dose sensitivity. The irradiation of M...

Background: In this study the basic radiation properties of N-isopropylacrylamaide polymer gel dosimeter were determined together with verification of its soft tissue equivalency. Materials and Methods: The NIPAM gel was prepared and irradiated approximately 2 h after manufacturing. The magnetic resonance (MR) images were made 24 h after irradiation. The nuclear magnetic resonance (NMR) respons...

context: to evaluate treatment success and hypothyroidism following main methods of radioiodine therapy of toxic nodular goiter (tng); calculated versus fixed dose and high versus low dose of radioiodine. evidence acquisitions: we searched medline and scopus databases from inception till july 2013, for clinical trials that compared two different methods of radioiodine administration in tng. the...

the adaptive response (ar) is a phenomenon by which cells exposure to sublethal doses of dna-damaging agents (non-mutagenic dose of chemical or radiation), known as conditioning treatment (ct), leads to increased resistance to a subsequent exposure to a higher dose of the same or other agents, known as challenge treatment (cr). the adaptive response (ar) induced by radiation in human lymphocyte...

background : there are growing evidences for chromosomal radioadaptive response in human lymphocytes . highly variable inter- and intra-individual responses have been reported. some individuals are non-responders and even in some donors the frequency of chromatid aberrations induced by a challenge dose increases by pre-exposure to an adapting dose. it has been proposed that the lack of radioada...

We develop tools from computational algebraic geometry for the study of steady state features of autonomous polynomial dynamical systems via elimination of variables. In particular, we obtain nontrivial bounds for the steady state concentration of a given species in biochemical reaction networks with mass-action kinetics. This species is understood as the output of the network and we thus bound...

Background: Some operating room personnel are occupationally exposed to genotoxic agents such as anesthetic gases and ionizing radiation. Adaptive response, as a defense mechanism, will occur when cells become exposed to a low dose of factors harming DNA (priming dose), which in the subsequent exposure to higher dose of those factors (challenging dose), show more resistance and sensibility.. <b...

Background: 7-LiF: Mg,Cu,P (GR-207A) is one kind of thermo-luminescent dosimeters (TLD) which can be used in diagnostic radiology and radiotherapy applications. Because of having suitable properties such as good sensitivity, small size and being tissue equivalent, thermo-luminescent dosimetry has been one of the most important techniques in medicine over many years. Choosing a correct energy fo...

Background: Radiation-sensitive polymer gels are among the most promising three-dimensional dose verification tools and tissue-like developed to date. Among the special features of this type of dosimeters, is be doped with other elements or chemicals which made them appropriate for investigating of dose enhancement with contrast agents, by high atomic number. Material and Methods: In this study...