In the last decades, treatment planning for multicatheter interstitial breast brachytherapy has evolved considerably from fluoroscopy-based 2D to anatomy-based 3D planning. To plan the right positions of the catheters, ultrasound or computed tomography (CT) imaging can be used, but the treatment plan is always based on postimplant CT images. With CT imaging, the 3D target volume can be defined ...

Introduction ...........................................................103 IMRT or 3DCRT? ...................................................105 The MSKCC IMRT Planning Process....................107 Patient Selection • Patient Simulation And Structure Localization • Selection Of Beam Energy, Number, And Direction • Optimization • Conversion Of Intensity Profiles To Leaf Motion • Forward Dose ...

Robust optimization of intensity-modulated proton therapy (IMPT) takes uncertainties into account during spot weight optimization and leads to dose distributions that are resilient to uncertainties. Previous studies demonstrated benefits of linear programming (LP) for IMPT in terms of delivery efficiency by considerably reducing the number of spots required for the same quality of plans. Howeve...

PURPOSE To investigate the critical structure sparing achievable by biological optimization for modulated volumetric arc (VMAT) of head and neck (H&N) cancer. METHODS Ten H&N VMAT patients who were originally planned and treated with simultaneous integrated boost technique using dose-volume based optimization, were selected. For each patient, a new VMAT plan was generated using the generalize...

Two intensity modulation radiotherapy (IMRT) delivery systems, the "step & shoot" multileaf collimator (MLC) auto-sequence and the use of an intensity modulator, are compared with emphasis on the dose optimization quality and the treatment irradiation time. The intensity modulation (IM) was created by a dose gradient optimization algorithm which maximizes the target dose uniformity while mainta...