Pharmacokinetic parameters are important for calculating the absorbed dose; they also provide an indirect measure of in vivo stability a radiopharmaceutical. The aim study was to determine excretion rate activity 177 Lu-DOTA-PSMA-617 and MCA 5–10 microns, 188 Re, from blood urine patients undergoing systemic local radiotherapy clinical trials. Materials methods: involved radiometry samples 12 m...

Two samples of a manual 3 L calibrating syringe which displays an electronically calculated FEF25-75% were evaluated to determine its suitability as a flow calibrator were evaluated. Room air was discharged into a manual spirometer system known to be accurate. The calibrator-determined values correlated very closely with the spirometer values over an FEF25-75 % range of 0.4 to 9 L/sec. The diff...