Recently we have shown how molecular logic circuits with many components arranged in multiple layers can be built using DNA strand displacement reactions. The potential applications of this and similar technologies inspire the study of the computation time of multilayered molecular circuits. Using mass action kinetics to model DNA strand displacement-based circuits, we discuss how computation t...

Striatal role in food motivation 3

DNA circuit is a versatile and highly-programmable toolbox which can potentially be used for the autonomous sensing of dynamic events, such as biomolecular interactions. However, the experimental implementation of in silico circuit designs has been hindered by the problem of circuit leakage. Here, we systematically analyzed the sources and characteristics of various types of leakage in a split ...

Background: The protein p53 has a well established role in protecting genomic integrity in human cells. When DNA is damaged p53 induces the cell cycle arrest to prevent the transmission of the damage to cell progeny, triggers the production of proteins for DNA repair and ultimately calls for apoptosis. In particular, the p53-Mdm2 feedback loop seems to be the key circuit in this response of cel...

this paper presents a new arc starter circuit that is usable in manual metal arc welding (mma) power supplies. the proposed circuit uses an auxiliary circuit and a series coupling transformer for adding high frequency spikes to output dc voltage during arc striking. the proposed circuit is usable in inverter based arc welding supplies and it could result in a decrease of weigh, volume and expen...

After Adleman and Lipton have described the potential power of DNA computing, researchers have developed an interest in DNA computing for solving difficult computational problems like NP-complete problems. Partitioning of digital circuits also come under this category. Partitioning plays a key role in the design of a computer system. Existing conventional methods are unable to achieve the requi...