Androgenetic alopecia and alopecia areata are common disorders of the hair follicle which may heavily influence self esteem and self image. Androgenetic alopecia is caused by the heightened sensitivity of scalp follicles to dihydro- testosterone whereas alopecia areata is induced by an autoimmune reaction. Current drug treatment approaches include the use of regrowth stimulators such as topical...

Herein, we demonstrate a facile methodology to synthesis a novel methacrylic phosphonic acid (PA)-functionalized polyhedral oligomeric silsesquioxanes (POSSs) via thiol-ene click reaction using octamercapto thiol-POSS and ethylene glycol methacrylate phosphate (EGMP) monomer. The presence of phosphonic acid moieties and POSS-cage structure in POSS-S-PA was confirmed by Fourier transform infrare...

The cutaneous sequelae of burns are usually temporary loss of pigment, hypertrophic scar and keloid. Infrequently skin neoplasia such as squamous cell carcinoma, basal cell carcinoma, malignant melanoma and sarcoma develop within the burn scar. Because ILVEN was developed after a burn in our patient, it is suggested that the possible mechanism for the development of ILVEN may have been that the...

The aim of this contribution is the application of matrix-assisted laser desorption/ionization mass spectrometric imaging (MALDI-MSI) in the area of photolithographic structuring. As proof of concept, this method was used to image an UV exposed negative photoresist layer, which is generally used to manufacture printed circuit boards (PCB) for electronic components. The negative photoresist laye...

Psoriasis is a common disease in children and adolescents. Because of the chronic course of the disease, appropriate choice of therapy in particular stage of the disease, so-called rotation therapy, is of paramount importance. This article provides a review of therapeutic options for childhood psoriasis. Local therapy for psoriasis in children consists of corticosteroid preparations, calcipotri...

Psoriasis is a chronic condition which causes the inflammation of the skin due to the activation of immune system leading to abnormal keratinocytes proliferation. The keratinocytes mature within a week as compared to normal cycle of 27 to 28 days. The oldest of the treatment includes the use of coal tar, Dithranol, sunlight, Dead Sea salts and emollients. Dermatologists now have a host of new t...

Psoriasis is a common, chronic, relapsing, papulo-squamous dermatitis, with overlying silvery scales. Psoriasis is an autoimmune disease. Genetic and environmental factors play a important role in psoriasis. The most commonly affected sites are the scalp, elbows, knees, umbilicus, genitalia, sacrum and shins. Psoriasis affects 3% of the population of the world. First-line treatments are topical...

We studied the effect of tacalcitol (1 alpha, 24 dihydroxy vitamin D3) ointment on clinical and immunohistochemical efficacy in psoriatic patients during 2 months of treatment. The psoriasis area and severity index decreased significantly after only 1 month and the total body surface index decreased 55% after 2 months. To characterize the epidermal compartment keratin 14, keratin 16, epidermal ...