The ability of irradiated tissue to support bony growth remains poorly defined, although there are anecdotal cases reported showing mixed results for the use of mandibular distraction osteogenesis after radiation for head and neck cancer. Many of these reports lack objective measures that would allow adequate analysis of outcomes or efficacy. The purpose of this experiment was to utilize a rat ...

Distraction osteogenesis is used both for leg lengthening and for bone transportation in the treatment of fractures and nonunions. The main problem with this method is that the time until full recovery may be up to a year, partly because of the time needed for the new formed bone to consolidate and become strong enough for weight bearing. We have studied whether intermittent parathyroid hormone...

BACKGROUND Bifocal distraction osteogenesis has been shown to be a reliable method for reconstructing segmental mandibular defects. However, there are few reports regarding the occurrence of inferior alveolar nerve regeneration during the process of distraction. Previously, we reported inferior alveolar nerve regeneration after distraction, and evaluated the regenerated nerve using histological...

BACKGROUND Changes over time in the callus during intermittent administration of parathyroid hormone (PTH) were studied in rabbit distraction osteogenesis models. METHOD Models of distraction osteogenesis in Japanese white rabbits were created, and distraction osteogenesis (total length: 10.5 mm) was performed for 2 weeks. Simultaneously with the start of distraction, 30 rabbits received 4 we...

PURPOSE The purpose of the present study was to evaluate the accuracy of navigation-assisted distraction osteogenesis of the mandible in a goat model. MATERIALS AND METHODS Six adult goats were included in the present study. A 3-dimensional (3D) image was reconstructed by performing computed tomography (CT) scans in 0.625-mm slices after placement of 5 maxillary marking screws and intermaxill...

Acquired thoracic dystrophy is a complication associated with early open repair of pectus excavatum resulting from extensive cartilage resection. The condition can cause serious functional and physiologic impairments, including cardiac compression and restrictive pulmonary function. We describe a 17-year-old boy with acquired thoracic dystrophy after Ravitch repair of pectus excavatum during in...

Majority of surgical experience with distraction technology has been in orthopaedics. Early results indicate the process to be equally effective in facial skeletal reconstruction. Distraction osteogenesis has proven to be a major advance for the treatment of several congenital and acquired mandibular deformities. A review of the literature dealing with distraction osteogenesis (DO) of the mandi...

Distraction osteogenesis is a treatment modality for the correction of bone anomalies and abnormalities which are either pathological or developmental in origin. Its use in the field of dentistry began in the late twentieth century. Successfulresults from clinical trials has led to more researchers to explore this field. Its use in dentistry involves the correction of craniofacial anomalies, al...

The localization and expression of neurotrophins and their receptors during distraction osteogenesis was investigated in 72 male rat femurs (11 weeks old) to further clarify the concurrence of cellular and molecular events of new bone formation. After osteotomy, a 7-day lag phase was followed by distraction at the rate of 0.25 mm/12 h for 21 days (distraction phase), and a 7-day consolidation p...