The efficiency of two biomass pretreatment technologies, dilute acid hydrolysis and dissolution in an ionic liquid, are compared in terms of delignification, saccharification efficiency and saccharide yields with switchgrass serving as a model bioenergy crop. When subject to ionic liquid pretreatment (dissolution and precipitation of cellulose by anti-solvent) switchgrass exhibited reduced cell...

Metformin hydrochloride is an orally administered first line drug which commonly used in the management of type-2 diabetes. To overcome the side effects of it due to high/repeated dose and patient inconvenience, the sustained release microparticles of metformin loaded RS100 were developed. The method used to prepared microparticles was novel oil in oil technique. Obtained microparticles were ch...

In Electrochemical Mechanical Planarization process (ECMP), concentrated phosphoric acid is usually used as electrolyte. Role of sodium dodecyl sulfate (SDS) in anodic dissolution of Cu in concentrated phosphoric acid was studied by Cyclic Voltammetry (CV), inhibition efficiency (IE) calculation and in-situ observation of the Cu electrode surface at anodic overpotentials. It was found that pres...

The use of natural polymers in the drug delivery continues to be an area of intensive research despite the advent of several new synthetic polymers. The present study envisages pharmaceutical utility of Assam glutinous rice as natural biopolymeric matrix for microfabricated controlled DDS. Microcarriers were prepared using an industrially feasible ionic gelation method using the blends of propo...

ABSTARCT : The objective of the study is to evaluate the individual main effects and combined (or interaction) effects of Hydroxy propyl β cyclodextrin (HPβCD), poly vinyl pyrrolidone (PVP K30) and sodium lauryl sulphate (SLS) on the solubility and dissolution rate of efavirenz in a series of 2 factorial experiments. The solubility of efavirenz in eight selected fluids containing HPβCD, PVP K30...

Benznidazole (BNZ) is traditionally used to treat Chagas disease. Despite its common use, BNZ has a poor water solubility and a variable bioavailability. The purpose of this study was to prepare BNZ microcrystals by solvent change precipitation and to study the effects of BNZ micronisation on therapeutic efficiency using a murine model of Chagas disease. The solvent change precipitation procedu...

This paper studies efficient partnership dissolution with ex post participation constraints in a setting with interdependent valuations. We derive a sufficient condition that ensures the existence of an efficient dissolution mechanism that satisfies Bayesian incentive compatibility, ex post budget balancedness, and ex post individual rationality. For equal-share partnerships, we show that our s...

Sulphur is an attractive cathode material with a high specific capacity of 1,673 mAh g(-1), but its rapid capacity decay owing to polysulphide dissolution presents a significant technical challenge. Despite much efforts in encapsulating sulphur particles with conducting materials to limit polysulphide dissolution, relatively little emphasis has been placed on dealing with the volumetric expansi...

The role of the crystal morphology and dissolution kinetics of Grubbs’ catalyst on self-healing capability is examined. Self-healing polymers require complete coverage of the crack plane with polymerized healing agent for optimal recovery of mechanical integrity. Lack of catalyst leads to incomplete coverage, partial polymerization, and poor mechanical recovery. Catalyst availability is determi...

BACKGROUND AND THE PURPOSE OF THE STUDY The relative in vivo bioavailability and in vitro dissolution studies of three chemically equivalent amiodarone generic products in healthy volunteers was evaluated in three separate occasions. The possibility of a correlation between in vitro and in vivo performances of these tablet formulations was also evaluated. METHODS The bioequivalence studies we...