background different clinical and epidemiological studies using dual-energy x-ray absorptiometry have shown an increased prevalence of low bone mineral density in patients with inflammatory bowel diseases.the aim of this study was to assess the correlation between bone density and the disease activity in patients with ulcerative colitis. methods in this cross-sectional study, 52 patients with u...

background: paraoxonase-1(pon1), a high-density lipoprotein (hdl) associated enzyme, is believed to contribute in the patho­genesis of coronary artery disease (cad). the aim of this study was to evaluate the association of pon1 promoter c (-107)t polymorphism with the extent of coronary artery stenosis in iranian patients. methods : the rflp analysis for determination of the c(-107)t genotype d...

background: occupational contact dermatitis, especially in hand, is one of the most common occupational disorders. the present study aimed at evaluating patients with occupational allergic contact dermatitis (acd) caused by common allergens based on occupation type and disease history.   methods: this cross-sectional study aimed at evaluating the data of the patients with probable diagnosis of ...

Background: Psoriasis is a chronic-relapsing inflammatory skin disorder, in whose pathogenesis oxidative stress is suggested to be involved. Among different enzymes that play a role in maintaining the cellular redox balance, we aimed to assess the alteration of glutathione peroxidase (GPX) activity in cutaneous lesions and its correlation with the disease severity, firstly, to support the possi...

Objective: Nigella sativa (NS) is a herbal medicine with anti-inflammatory and anti-oxidant functions. This study was designed to evaluate the effect of oral administration of NS seeds oil on the treatment of Behcet’s disease (BD). Materials and methods:In this double-blind randomized controlled study, 130 patients with BD were screened and 71 patients with BD were randomly allocated to the tre...

Background and Objective: Rheumatoid arthritis (RA) is an autoimmune disease defined by chronic synovitis and progressive joint destruction. This study investigated calprotectin as a serological marker in the hope of establishing an adequate means of diagnosing RA and following up on patients. Materials and Methods: This cross-sectional study included 32 RA patients who were referred to the rh...

background systemic lupus erythematosus (sle) is an autoimmune connective-tissue disease involving multiple organs and systems. some evidence has demonstrated that disease activity could be associated with increased risk of organ damage. objectives the aim of this study was to determine the association between systemic lupus erythematosus disease activity index (sledai) scores and subclinical c...

Background: Occupational contact dermatitis, especially in hand, is one of the most common occupational disorders. The present study aimed at evaluating patients with occupational allergic contact dermatitis (ACD) caused by common allergens based on occupation type and disease history.   Methods: This cross-sectional study aimed at evaluating the data of the patients with probable diagn...

antineutrophil cytoplasmic autoanibodies (anca) were detecte in patients with certain autoimmune vascular disease such as wegner’s granulomatosis, polyarthrits nodosa and systemic luuc erythematous. indirect immunofluorescence (iif) technique was employed to detec these autoantibodies.anca have been recently detected in some forms of inflammatory bowel disease (ibd), ulcerative colitis (u.c). c...

vitamin d3 has a role in many autoimmune diseases and appears to play a function in controlling rheumatoid arthritis (ra). the aim of this study is to evaluate the relationship between serum level of vitamin d and ra disease activity score. the serum level of vitamin d in 75 ra patients referred to the rheumatology clinic of rasoul-akram hospital was measured. patients were classified into low,...