Toll-like receptor 4 (TLR4) is considered to have a critical role in the occurrence and development of atherosclerosis in atherosclerosis-prone mice; however, it remains uncertain whether treatment with a TLR4 inhibitor may attenuate atherosclerosis. The present study aimed to determine the vascular protective effects of the TLR4 inhibitor CLI-095 on apolipoprotein E‑deficient (ApoE‑/‑) mice. A...

Introduction: In this study, the authors aimed to examine theeffects of cooperative learning methods using Web Quest andteam-based learning on students’ self-direction, self-regulation,and academic achievement.Methods: This is a comparative study of students taking a course inmental health and psychiatric disorders. In two consecutive years,a group of students were trained using the Web Quest a...

Introduction: Online formative assessments (OFA’s) have beenincreasingly recognised in medical education as resources thatpromote self-directed learning. Formative assessments are usedto support the self-directed learning of students. Online formativeassessments have been identified to be less time consuming withautomated feedback. This pilot study aimed to determine whetherparticipation and pe...

conclusions: implementation of self-directed learning provides a useful strategy that should be included in health intervention and national surveillance programs in order to improve health and therapeutic compliance in postmenopausal women. results: there were significant statistical differences between two groups regarding the age of subjects; age of menopause; economic, educational and emplo...

multi agent markov decision processes (mmdps), as the generalization of markov decision processes to the multi agent case, have long been used for modeling multi agent system and are used as a suitable framework for multi agent reinforcement learning. in this paper, a generalized learning automata based algorithm for finding optimal policies in mmdp is proposed. in the proposed algorithm, mmdp ...

Faculty of Medical Sciences, Pontifical Catholic University of São Paulo – PUC-SP, CEP 18030-095, Sorocaba, SP, Brazil Department of Physiological Sciences, Faculty of Medical Sciences, Pontifical Catholic University of São Paulo – PUC-SP, CEP 18030-095, Sorocaba, SP, Brazil Department of Materials Engineering, Faculty of Mechanical Engineering, State University of Campinas – UNICAMP, CEP 13083...