نتایج جستجو برای: direct mutagenesis
تعداد نتایج: 451037 فیلتر نتایج به سال:
word count: 178 Manuscript word count: 4936 Blood First Edition Paper, prepublished online June 16, 2005; DOI 10.1182/blood-2004-12-4840 Copyright © 2005 American Society of Hematology only. For personal use at PENN STATE UNIVERSITY on February 23, 2013. bloodjournal.hematologylibrary.org From
We developed several novel tools to genome wide screen for CNVs and SNPs in single cells. When applied to cleavage stage embryos from young fertile couples we discovered, unexpectedly, an extremely high incidence of chromosomal instability, a hallmark of tumorigenesis (Vanneste et al., Nature Medicine, 2009; Vanneste et al., Hum.Reprod., 2011). Not only mosaicisms for whole chromosome aneuploid...
The global pollution of environment urges the screening effective natural protectors for correc-tion toxic and genotoxic action xenobiotics. Medicinal herbs contain a complex biologically ac-tive compounds that are potential sources such protective agent. In current study mutagenic antimutagenic activity alcoholic extracts peppermint (Mentha piperita L.) thyme (Thymus vulgaris L.), family Lamia...
Purple rice (Oryza sativa L. var. indica) cv. Kum Doisaket is cultivated in northern Thailand. This study evaluated the mutagenic and antimutagenic properties of hydrophilic and lipophilic components of purple rice using the Ames test. The seed and hull of purple rice were extracted with hexane, methanol, ethanol, and water. The methanol extracts had the highest amounts of phenolic acids and fl...
ددر این تحقیق استفاده از کربن اکتیو ، ذرات نانو مغناطیسی آهن و ذرات نانو کامپوزیت آهن- کربن اکتیو، برای حذف رنگ آنیونی از پسابهای سمی مورد مطالعه قرار گرفتند . رنگ direct orange -26 به عنوان مدلی از رنگ آنیونی مورد بررسی قرار گرفت. مشخصات سطحی نانو ذرات آهن و نانو کامپوزیت آهن توسط sem مورد بررسی قرار گرفت . تاثیر عوامل مختلف (ph ، دوز جاذب، زمان تماس، دور هم زدن) به روش طراحی آزمایش تاگوچی مور...
rested on sociocultural theory (sct), this study attempted to examine the effect of written corrective feedback (wcf) followed by producing written languaging on developing writing accuracy over new tasks. to this aim, two intact iranian efl classes at the low-intermediate level were randomly assigned to two experimental groups: direct (n = 25) and indirect (n = 25). both groups wrote on a numb...
current studies in second language (l2) learning have revealed the positive role of corrective feedback (cf) in both oral and written forms in different language features. the present study was an attempt to investigate the effect of both direct and indirect written corrective feedback (wcf) on the use of grammatical collocations in l2 writing. the study also sought to examine whether the effec...
β-Lactoglobulin (BLG) like other lipocalins can be modified by mutagenesis to re-direct its ligand binding properties. Local site-directed was used change the geometry of BLG pocket and therefore preferences. The presented studies are focused on previously described mutants L39Y, I56F, L58F, F105L, M107L two new variants, L39K F105A, their interactions with local anesthetic drug tetracaine. Bin...
Rad27/FEN1 nuclease that plays important roles in the maintenance of DNA stability in the nucleus has recently been shown to reside in mitochondria. Accordingly, it has been established that Rad27 deficiency causes increased mutagenesis, but decreased microsatellite instability and homologous recombination in mitochondria. Our current analysis of mutations leading to erythromycin resistance ind...
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