FTER THE pioneer work of the French School in the study of acquired hemolytic anemia ( Hayem,’ Chauffard,2 WidaP ) , and the demonstration of hemolysins 30 years later by Dameshek and Schwartz,4 Boorman, Dodd and Loutit5 demonstrated the presence of a positive direct antiglobulin test. Thus, the immunologic origin of some of these cases has been gradually clarified, although many aspects of the...

In vivo coating of red cells by antibody and/or complement is detected using various sensitive techniques, however most hospitals even today rely on the conventional tube technique (CTT). We compared the performance of the CTT and recently introduced gel test (GT) in the evaluation of direct antiglobulin test (DAT). The CTT and GT were first compared using in-house prepared control cells. The p...

INTRODUCTION The objective of the analysis was to examine the epidemiological aspects of maternal alloimmunization and to determine the most common antibody specificities resulting in hemolytic disease of the newborn (HDN). MATERIALS AND METHODS The retrospective epidemiological study encompasses all pregnant women who underwent immunohematological screening and the newborn treated for HDN in...

Even though clinical features in autoimmune haemolytic anaemia vary according to the type of AIHA, anaemic syndrome stays common for most cases. A positive Coombs test or direct anti-globulin developed 1945 by Coombs, Mourant and Race, is deciding factor AIHA diagnosis. Since immunologic mechanisms causing erythrocyte destruction between AIHAs, treatment also different. Empirical approach with ...

Case Report Mrs. Vail is group 0, Rh-negative, Duffy-negative; her husband, group 0, Rh-negative, Duffy-positive. Mr. Vall is 0; MsNs; P+; cdE.cde; kk; Fy(a+); Le(a-). Mrs. Vall is 0; NsNs; P+; cde.cde; Kk; Fy(a-); Le(a-); Jk(a+). Baby is 0; NsNs; P+; cde.cde; kk; Fy(a+); Le(a-). Mrs. Vail's pregnancy record is as follows: (1) In 1949, normal. The mother was transfused immediately following thi...

The immune states of 52 patients with myelodysplastic syndromes classified according to the FAB criteria were studied. Serum electrophoresis and immunoelectrophoresis, direct Coombs test, and tests for organ and non-organ specific antibodies were performed. Twenty six patients had immunoglobulin abnormalities: six (11.5%) had monoclonal gammopathy; 17 (32.6%) had polyclonal increases in serum i...

OBJECTIVE To assess direct costs associated with ankylosing spondylitis (AS). To determine which variables, including country, predict costs. METHODS 216 patients with AS from the Netherlands, France, and Belgium participated in a two year observational study and filled in bimonthly economic questionnaires. Disease related healthcare resource use was measured and direct costs were calculated ...

BACKGROUND Recent studies have suggested that electroencephalogram (EEG) bispectral index (BIS) monitoring can improve recovery after anaesthesia and save money by shortening patients' postoperative stay. We wanted to evaluate the direct costs of BIS monitoring and to measure immediate recovery after anaesthesia in patients with or without BIS monitoring. METHODS Eighty patients undergoing gy...

IgG3 type. The hematic and serous blood group was identified as 0 Rh positive; anti-DNA and ANA antibodies were negative. Viral serology demonstrated IgM anti-varicella antibodies, anti-HIV, CMV, infectious mononucleosis and hepatitis serelogy was negative. An immunohematological study carried out at the regional transfusion center showed the 3+/4+ positivity for the direct Coombs’ test with th...