spectrophotometric and electrochemical studies were successfully used in quantitative analysis of amitriptyline hydrochloride (ath) and nortriptyline hydrochloride (nth). conductometric titration were carried out in equeous solution using iodide and dopamine and serotonine as titrant. two new methods using spectrophotometry are dascribed for the determination of (ath) and (nth) with potassium b...

1 N-Isopropyl-p-iodoamphetamine hydrochloride (IMP) is predominantly metabolized by CYP2C19

A new selective medium (PC agar) for the isolation of Pseudomonas aeruginosa was developed, consisting of 30 micrograms of 9-chloro-9-[4-(diethylamino)phenyl]-9,10-dihydro-10-phenylacridine hydrochloride (C-390) per ml and 30 micrograms of phenanthroline per ml in Columbia agar. PC agar was superior to phenanthroline, C-390, acetamide, and cetrimide agars for the selective growth of P. aeruginosa.

The problem of determining the arrangements of atoms in crystals directly from X-ray diffraction data has engaged the attention of crystallographers for some time, and a number of approaches to this general problem have been presented. We have been especially interested in the approach which makes use of imageseeking functions in solving the Patterson synthesis,' which, in turn, is based entire...

We here describe a new spectrophotometric method for measuring total bilirubin in serum. The method is based on the cleavage of bilirubin giving formaldehyde which further reacts with diazotized 3-methyl-2-benzothiazolinone hydrazone hydrochloride giving blue colored solution with maximum absorbance at 630 nm. Sensitivity of the developed method was compared with Jendrassik-Grof assay procedure...

Mental health is an important medical issue in perinatal care, and there is increasing evidence that insomnia during pregnancy is associated with postpartum depression (PPD). Therefore, the present study evaluated the effect of insomnia treatment during the third trimester of pregnancy on PPD symptoms. Fifty-four pregnant women with insomnia were randomly assigned to trazodone, diphenhydramine,...

OBJECTIVES This study was done to compare isoxpurine hydrochloride and nifedipine as tocolytic drugs for preterm labor. METHODS A prospective cohort study of 832 antenatal women with preterm labor was conducted in the Department of Obstetrics & Gynecology. Out of 400 women found eligible for tocolysis, 200 were given isoxpurine hydrochloride while the other 200 were given nifedipine randomly....

OBJECTIVE To evaluate the effects of oral administration of diphenhydramine on pupil diameter, intraocular pressure (IOP), tear production, tear film quality, corneal sensitivity, and conjunctival goblet cell density (GCD) in clinically normal adult dogs. ANIMALS 12 healthy adult dogs. PROCEDURES All dogs received diphenhydramine (2.2 mg/kg, PO, q 12 h) for 21 days. Conjunctival biopsy samp...