We investigated the properties of an artificial chimeric peptide that contains an Arg-Gly-Asp (RGD)tripeptide, the versatile cell recognition signal of extracellular matrix protein components, coupled to a carboxyl-terminal fragment of the highly specific a-thrombin hibitor, hirudin (residues 53-64): WG-SANGDFEEIPEEYL (RGD-hir~din'~-'~). Hir ~ d i n ~ ~ ' ~ and RGD-hir~din'~-'~ inhibited th...

Incidental ingestion of household dust is an important arsenic (As) exposure pathway for children. However, compared to soils, assessment of As relative bioavailability (RBA) in household dust is limited. In this study, As-RBA in 12 household dust samples (7–38 mg kg(–1)) was measured using an in vivo mouse model and compared to As bioaccessibility determined using 4 assays [Solubility Bioacces...

Availability and leaching of dissolved inorganic N (DIN = NH4 + NO3) in soil were measured in a periodically flooded forest of the Central Amazon floodplain (v rzea) during one terrestrial phase. Special emphasis was on the effects of a legume and a nonlegume tree species. NH4-N accounted for more than 85% of DIN even at the end of the terrestrial phase although it decreased throughout the expe...

BACKGROUND Sponges have long been known to be ecologically important members of the benthic fauna on coral reefs. Recently, it has been shown that sponges are also important contributors to the nitrogen biogeochemistry of coral reefs. The studies that have been done show that most sponges are net sources of dissolved inorganic nitrogen (DIN; NH4 (+) and NO3 (-)) and that nitrification, mediated...

Monthly time series of nutrient pools and transport in the Baltic Entrance were computed for the period 1974–1999 from a combination of hydrodynamic model results and observational data obtained in national monitoring programmes. Significant seasonal variations in both nutrient pools and transport were found. For example, inflowing dense nutrient-rich Skagerrak water causes net transport of dis...

Relatively high deposition of nitrogen (N) in the northeastern United States has caused concern because sites could become N saturated. In the past, mass-balance studies have been used to monitor the N status of sites and to investigate the impact of increased N deposition. Typically, these efforts have focused on dissolved inorganic forms of N (DIN = NH4-N + NO3-N) and have largely ignored dis...

Spaţiile virtuale 3D devin din ce în ce mai mult utilizate, de la jocuri până la aplicaţii industriale, medicale, militare sau ştiinţifice. Unele dintre cele mai importante aplicaţii ale acestora sunt în e-learning şi edutainment. Lucrarea de faţă prezintă elementele constitutive şi aspecte ale creării unui”muzeu virtual 3D”, pornind de la experienţa autorilor în dezvoltarea aplicaţiei software...

Rezumat: Sănătatea fizică și psihică bună reprezintă indubitabil unele dintre cele mai prețioase calități pe care le poate poseda o persoană. Fără aceste elemente, orice activitate simplă devine un efort iar orice efort devine o imposibilitate. Astfel, o mare parte din populația din România care se prezintă în camera cu gardă cu stare generală alterată dată de hipertensiunea arteriala (HA) rapo...

BACKGROUND Ductal intraepitelial neoplasia (DIN) represents a spectrum of disease that may progress from usual hyperplasia to ductal carcinoma in situ (DCIS) grade 3. The aim of the study was to asses the correlation between the DIN classification and the surgical treatment including sentinel lymph node biopsy (SLNB). PATIENTS AND METHODS In this retrospective study, 229 patients with DIN had...

[1] To assess the effects of increased atmospheric N input on N availability in ombrotrophic peatlands, the relative concentrations of dissolved organic nitrogen (DON) to dissolved inorganic nitrogen (DIN) were measured in bog waters along a natural gradient of atmospheric N deposition. Six European bogs were selected, spanning a range of chronic atmospheric N inputs from 0.2 to 2.0 g m 2 yr . ...