MR 2 variety mulberry leaves were sterilized with UV light for 5, 10 and 15 minutes. These leaves were fed to PM x NB 4 D 2 hybrid silkworm Bombyx mori Linn. life stages and recorded the macromolecular contents (total protein, reducing sugar and glycogen) and digestive enzymes (amylase, invertase and protease) activities. Results revealed feeding of silkworm B. mori with UV treated mulberry lea...

GASTRIC STABILITY STUDY OF SUPPLEMENTAL DIGESTIVE ENZYMES In order to meet the cellular demands of adequate nutrients, there must be a good selection of the foods containing the nutrients and also a good digestion/absorption within the gastrointestinal tract. This awareness to ensure good bioavailability of nutrients is gaining more interest. As a result, the administration of supplemental dige...

Human immunodeficiency virus type 1 (HIV-1) protease inhibitors comprise an important class of drugs used in HIV treatments. However, mutations of protease genes accelerated by low fidelity of reverse transcriptase yield drug resistant mutants of reduced affinities for the inhibitors. This problem is considered to be a serious barrier against HIV treatment for the foreseeable future. In this st...

Excessive ethanol consumption is a common risk factor for acute and chronic pancreatitis. Ethanol could lead to the onset of pancreatitis in a number of ways; the most recently discovered is its effect on intrapancreatic digestive enzyme activation, by either sensitizing acinar cells to pathologic stimuli or stimulating the release of a secretagogue (cholecystokinin) from duodenal I cells. Rece...

This review focuses on phytase functionality in the digestive tract of farmed non-ruminant animals and the factors influencing in vivo phytase enzyme activity. In pigs, feed phytase is mainly active in the stomach and upper part of the small intestine, and added phytase activity is not recovered in the ileum. In poultry, feed phytase activities are mainly found in the upper part of the digestiv...

Ontogenetic changes in dry weight, elemental composition (CHN), and digestive enzyme activities (total protease, amylase) were studied during the moulting cycle of all larval instars (zoea I-II, megalopa; ZI, ZII, M) of the spider crab Maja brachydactyla Balss, 1922 reared in the laboratory. A gradual but significant increase in biomass was observed throughout the zoeal instars, followed by ste...

Digestive enzymatic activity in three geographic strains (Miandiab, Kalposh and Moghan regions) of Spodoptera exigua (Hübner) (Lepidoptera: Noctuidae) reared on different sugar beet cultivars (Dorothea, Rozier, Persia and Perimer) was studied under laboratory conditions (25 ± 1 °C, 65 ± 5% RH, and a photo period of 16:8 (L:D) h photoperiod). The results of this study demonstrated that digestive...

The mechanism by which digestive zymogens become activated during acute pancreatitis remains poorly understood. Given the ability for cholecystokinin (CCK) to induce pancreatitis in vivo, the effects of high dose CCK on preparations of isolated pancreatic acini were examined. Using an immunologic technique for the detection of zymogen activation, CCK was found to stimulate the conversion of pro...

To invade its definitive host, the mosquito, the malaria parasite must cross the midgut peritrophic matrix that is composed of chitin cross-linked by chitin-binding proteins and then develop into an oocyst on the midgut basal lamina. Previous evidence indicates that Plasmodium ookinete-secreted chitinase is important in midgut invasion. The mechanistic role of other ookinete-secreted enzymes in...