Diffusion-weighted (DW) magnetic resonance imaging (MRI) is the only technique that permits a non-invasive in vivo assessment of water molecular diffusion, which reflects tissue configuration at a microscopic level. Therefore, this technique appears to be particularly useful in monitoring brain abnormalities. However, the quantitative measurement of diffusion is not without problems, which may ...

Diffusion-weighted magnetic resonance imaging (DW-MRI) is a recognized tool for early detection of infarction of the human brain. DW-MRI uses the signal loss associated with the random thermal motion of water molecules in the presence of magnetic field gradients to derive parameters that reflect the translational mobility of the water molecules in tissues. If diffusion-weighted images with diff...

BACKGROUND AND PURPOSE Ischemic tissue damage is heterogeneous, resulting in complex patterns in the widely used diffusion-weighted MRI. Our study examined the spatiotemporal characteristics of diffusion kurtosis imaging in an animal model of transient middle cerebral artery occlusion. METHODS Adult male Wistar rats (N=18) were subjected to 90 minutes middle cerebral artery occlusion. Multipa...

BACKGROUND Accurate localization of acute ischemic lesions in patients with an acute stroke may aid in understanding the etiology of their stroke and may improve the management of these patients. OBJECTIVE To determine the yield of adding diffusion-weighted magnetic resonance imaging (DWI) to a conventional magnetic resonance imaging (MRI) protocol for acute stroke. DESIGN A prospective coh...