primary hepatic lymphoma (phl) is rare and possibly associated with viral hepatitis and autoimmune diseases. scleroderma could exceptionally be complicated by lymphoma. we describe phl occurring in a 52-year-old female suffering scleroderma for eight years, with no history of cytotoxic or high-dose glucocorticoid therapy. ct scan, performed to work-up abdominal discomfort, constipation, and ele...

  Background and Objective: Approximately half of patients with diffuse large B-cell lymphoma are cured with current chemotherapy regimens. The purpose of this study was to evaluate Bax and Bcl2 expression and their relationship with the response to chemotherapy. Materials and Methods This study was a prospective analysis on 44 patients with diffuse large B-cell lymphoma. Their specimens we...

Keywords Disease name and synonyms Differential diagnosis Frequency Definition Clinical description Etiology Genetic features Diagnostic methods Staging Prognostic parameters Treatment Survival Keywords References Abstract Primary diffuse large B-cell lymphomas (DLB-CL) are aggressive tumors accounting for approximately 40% of the B-cell malignancies. DLB-CL are commonly composed of a mixture o...

Diffuse large B cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma worldwide, representing approximately 30-40% of all cases in different geographic regions. Patients most often present with a rapidly growing tumour mass in single or multiple, nodal or extranodal sites. The most common type of DLBCL, designated as not otherwise specified, represents 80-85% of all cases and is...

Expert Panel on Radiation Oncology–Lymphoma: Bouthaina S. Dabaja, MD; Ranjana Advani, MD; David C. Hodgson, MD; Sughosh Dhakal, MD; Christopher R. Flowers, MD, MS; Chul S. Ha, MD; Bradford S. Hoppe, MD, MPH; Nancy P. Mendenhall, MD; Monika L. Metzger, MD; John P. Plastaras, MD, PhD; Kenneth B. Roberts, MD; Ronald Shapiro, MD; Sonali M. Smith, MD; Stephanie A. Terezakis, MD; Karen M. Winkfield, ...

the patient was a 67-year-old female who presented with severe rectal bleeding since three days prior to hospital admission. she complained of mild abdominal pain. rectal examination revealed the presence of fresh blood and a clot. she had a normal upper endoscopy. a colonoscopy showed a large clot with bloody secretions up to the cecum, with no obvious origin. because of the severity of bleedi...

BACKGROUND FoxM1 has been shown to play a critical role in the pathogenesis of various epithelial malignancies. However, its role in lymphoid malignancies has not been fully clarified. We, therefore, investigated the role of FoxM1 expression in a large cohort of diffuse large B-cell lymphoma samples and panel of cell lines. DESIGN AND METHODS FoxM1 expression was investigated in a large serie...