Sternocostoclavicular hyperostosis (SCCH) is a chronic osssifying diathesis affecting mostly juxtasternal structures and the inflammatory osteitis part of synovitis, acne, pustulosis, hyperostosis, (SAPHO) syndrome.

Recently, patients with hypohidrotic/anhidrotic ectodermal dysplasia (H/AED) have been reported to have a higher prevalence of symptoms suggestive of atopic disorders than the general population. To better understand atopic diathesis in H/AED, 6 cases of clinically or genetically diagnosed H/AED were examined. The following criteria were evaluated with patient consent: sweating, blood test resu...

Eosinophilic gastroenteritis is a rarely reported condition. The disease is characterized by peripheral blood eosinophilia, eosinophilic infiltration of the bowel wall to a variable depth, and gastrointestinal complaints. Allergic diathesis can be found in most of the cases. In this article we report two cases with interesting epidemiological characteristics and we will have a brief review ...

The syndrome produced by lesion of the septum in animals can serve as a functional research model of human disinhibitory psychopathology. Disinhibitory psychopathology appears to span several traditionally separate psychological categories—psychopathy, hysteria, hyperactivity, antisocial and impulsive personality, and alcoholism. It is proposed that these categories are separate manifestations ...

Platelet function disorder in the presence of normal platelet count has been reported to lead variable clinical phenotypes [1]. Differential diagnosis these bleeding diathesis types much more complex than thrombocytopenic conditions.

A stress-diathesis explanatory model of suicidal behaviour has proved to be of heuristic value, and both clinical and neurobiological components can be integrated into such a model. A trait deficiency in serotonin input to the anterior cingulate and ventromedial prefrontal cortex is found in association with suicide, and more recently non-fatal suicidal behaviour, and is linked to decision-maki...

Accurate prediction of suicide risk remains a challenge, in its prevention. Many people with psychiatric disorders do not manifest suicidal behaviour, suggesting the importance of diathesis, or susceptibility to suicide, in addition to associated disorders. At present there are no biomarkers to predict suicidal behaviour. The authors of this article have attempted to describe the neurobiology o...