نتایج جستجو برای: diabetic nephropathy
تعداد نتایج: 125565 فیلتر نتایج به سال:
conclusions therefore, our results suggest that although administration of 300 mg/kg of calendula officinalis extract showed salutary effects on anti-oxidant profile, yet its protective effects on anti-diabetic and regenerative properties on nephropathy were ambiguous and require more investigations. background chronic hyperglycemia leads to microvascular and macrovascular complications such as...
abstractintroduction: diabetes mellitus is the most common human metabolic disease and chronic non healing diabetic foot ulcers are a critical complication for these patients. angipars is a new herbal extract which has been introduced to accelerate healing of these ulcers. the purpose of this study was to investigate the efficacy and safety of oral angipars in patients with chronic diabetic foo...
background: early diagnosis of albuminuria and the prevention of its progression to macroalbuminuria and diabetic nephropathy are crucial. angiotensin converting enzyme inhibitors (aceis) and antagonists of angiotensin ii receptors type i (arbs) are currently used as first-line treatment for albuminuria in these patients. the present study was conducted to assess the efficacy of addition of spi...
effects of grape seed proanthocyanidin extract on oxidative stress induced by diabetes in rat kidney
background: this study examined the effect of grape seed proanthocyanidin extract (gspe) on lipid peroxidation content and activity of tissue antioxidant enzymes, including catalase, superoxide dismutase and glutathione peroxidase in diabetic rats. methods: thirty male rats were divided into three groups of 10 rats each: control, diabetic and diabetic groups that received 500 mg/kg gspe for 6 w...
OBJECTIVE Glomerular mesangial expansion and podocyte loss are important early features of diabetic nephropathy, whereas tubulointerstitial injury and fibrosis are critical for progression of diabetic nephropathy to kidney failure. Therefore, we analyzed the expression of genes in glomeruli and tubulointerstitium in kidney biopsies from diabetic nephropathy patients to identify pathways that ma...
Background: The aim of this study was to estimate the prevalence, severity, and risk factors for diabetic retinopathy in diabetic cases admitted for non-ocular diabetic complications and to investigate the association between retinopathy and these complications.Methods: In this cross-sectional study, 84 diabetic patients admitted to our university-affiliated hospital for non-ocular diabetic com...
Diabetic nephropathy is the leading cause of ESRD in high-income countries and a growing problem across the world. Vascular endothelial growth factor-A (VEGF-A) is thought to be a critical mediator of vascular dysfunction in diabetic nephropathy, yet VEGF-A knockout and overexpression of angiogenic VEGF-A isoforms each worsen diabetic nephropathy. We examined the vasculoprotective effects of th...
BACKGROUND Renal transplantation has been established as a treatment for end-stage renal disease (ESRD) due to diabetic nephropathy. However, few studies have focused on the outcome after renal transplantation in patients with ESRD and type 2 diabetic nephropathy. To investigate the effect of renal transplantation on ESRD with type 2 diabetic nephropathy, we retrospectively analyzed patients wh...
Introduction: Diabetic nephropathy is the most common cause of renal failure. High blood pressure, specially its glomerular type is one of the dominant factors in the development of nephropathy in diabetic patients. The present study evaluates the effects of Hibiscus Subdariffa on blood pressure and urinary albumin in patients with diabetic nephropathy. Methods: Current study was a double-bl...
Oxidative stress contributes to the pathogenesis of diabetic nephropathy. In mitochondria, lipoic acid synthase produces α-lipoic acid, an antioxidant and an essential cofactor in α-ketoacid dehydrogenase complexes, which participate in glucose oxidation and ATP generation. Administration of lipoic acid abrogates diabetic nephropathy in animal models, but whether lower production of endogenous ...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید