CONTEXT Hospitalized infants undergo repeated invasive procedures. It is unknown whether cumulative experiences with pain lead to anticipatory pain behaviors and hyperalgesia. OBJECTIVES To determine whether newborns who are born to mothers with diabetes and undergo repeated pain learn to anticipate pain and exhibit more pain during a painful procedure than normal infants. DESIGN, SETTING, ...

INTRODUCTION Since research investigating IGF-1 levels in breast milk are few, the goal of this study was to analyze the IGF-1 levels in the breast milk of diabetic mothers as well as in the serum of their newborn babies and to identify what relationship exists between blood serum and IGF-1 milk levels through patient measurement of mothers and their babies. METHODS This case control study wa...

BACKGROUND Previous studies have suggested that language is affected in infants of diabetic mothers, yet there have been no systematic investigations to address this question. OBJECTIVE Our goal was to compare infants of diabetic mothers and controls on language outcomes from ages 18 months to 7 years. METHODS This was a case-control longitudinal design with 2 birth cohorts: 1835 singletons...

OBJECTIVE To verify the hypothesis that the pulmonary vein pulsatility index is higher in fetuses of diabetic mothers than it is in normal fetuses of nondiabetic mothers. METHODS Twenty-four fetuses of mothers with either gestational or previous diabetes (cases), and 25 normal fetuses of mothers without systemic disease (control) were examined. Fetuses were examined through prenatal Doppler a...

BACKGROUND Infants of diabetic mothers (IDMs) are at increased risk for metabolic complications. Type 1 and some type 2 diabetic patients have elevated levels of the ketone bodies acetoacetate (AA) and β-hydroxybutyrate (BHB). OBJECTIVE The aim of this study was to examine how hyperketonemia in diabetic mothers affects markers of inflammation and oxidative stress in their offspring. METHODS...

Cord blood serum lipids are much lower than those of adults. Two recent studies of cord blood lipids of infants of diabetic mothers (Pantelakis, Cameron, Davidson, Dunn, Fosbrooke, Lloyd, Malins, and Wolff, 1964; Lloyd, 1963) suggest that certain lipid fractions are higher in these infants than in infants of normal mothers. In view of recent work suggesting that in diabetes mellitus a disturban...

conclusions we did not find significant differences in ventricular function or ventricular septal thickness in the fetuses of mothers who were referred to our hospital with a previous diagnosis of diabetes mellitus compared with the fetuses of non-diabetic mothers. this could be due to early identification, appropriate treatment, and tightly controlled diabetes in our study population. it shoul...

Background: The prevalence of gestational diabetes mellitus is rising. Myocardial hypertrophy is the most common cardiac disorder in the infants of diabetic mothers, which hypothetically can cause fatal arrhythmias. This study investigated prolonged QT in the newborns of diabetic mothers in Afzalipour Hospital in Kerman City, in 2015. Methods: This case-contro...