Abstract Background: Diabetes is a metabolic disorder with adverse effects on haematological parameters level, oxidative stress and antioxidant defence system. This study aimed to investigate the effects of Rosa canina (RC) fruit hydro alcoholic extract on oxidative stress, total antioxidant capacity (TAC) and haematological parameters in diabetic mice. <st...

Diabetic neuropathy is a nerve disorder manifested by different faceted condition affecting up to half of individuals with persistent diabetes. Symptoms associated this disease such as palsy, painful polyneuropathy, thoracoabdominal neuropathy, autonomic diabetic amyotrophy, mononeuropathy multiplex, caused motor, sensory, and dysfunction which affects peripheral nervous system, gastrointestina...

cinnamomum zeylanicum (cinnamon) has a wide range of beneficial effects including mild glucose lowering activity. the aim of the present study was to investigate whether cinnamon bark extract has the potential to improve memory performance and glucose profiles in diabetic mice. memory was assessed by the novel object recognition task in male balb/c mice. in this method, the difference between e...

ABSTRACT For a long period, ethno medicinal plants have been a valuable source of natural products for maintaining human health, especially in the last decade, with more intensive studies for natural therapies. The use of ethno medicinal plant for pharmaceutical purposes has gradually increased in Iran. Gundelia tournefortii has been used as an antibacterial, anti-fungal, antipyretic, anti-in...

For a long period, ethno medicinal plants have been a valuable source of natural products for maintaining human health, especially in the last decade, with more intensive studies for natural therapies. The use of ethno medicinal plant for pharmaceutical purposes has gradually increased in Iran. Gundelia tournefortii has been used as an antibacterial, anti-fungal, antipyretic, anti-inflammatory,...

We examined the endothelial gap junctions in diabetic hyperlipidemic mice. Male apolipoprotein E (apoE)-deficient mice were made diabetic by streptozotocin. Three weeks later, the animals were treated with simvastatin for 2 weeks. The expression of aortic gap junctions in the non-diabetic (n=10), untreated diabetic (n=10), and simvastatin-treated diabetic animals (n=6) was analyzed. There was a...

Podocyte loss was well known in type 2 diabetic nephropathy patients. The objective of the present study was to determine the number of podocytes and the degree of albuminuria in diabetic KK-A/Ta (KK-A) mice which had been reported as diabetic nephropathy model. Diabetic KK-A mice, diabetic KK/Ta mice and nondiabetic BALB/cA Jcl (BALB/cA) mice were studied. We analyzed glomerular lesions in all...

Background: Diabetes is a metabolic disorder that in long period can damage the testis and reduce the semen quality. Therefore, it can impair the male fertility potential. Recently, different herbal therapeutic treatment for protection of diabetes and its pathologic effects have been used. The aim of current study is to evaluate the protective effect of Equisetum arvense extract (EE) on in vitr...

For a long period, ethno medicinal plants have been a valuable source of natural products for maintaining human health, especially in the last decade, with more intensive studies for natural therapies. The use of ethno medicinal plant for pharmaceutical purposes has gradually increased in Iran. Gundelia tournefortii has been used as an antibacterial, anti-fungal, antipyretic, anti-inflammatory,...