Multiple risk factors interplay in the formation of foot ulceration and/or limb amputation in the diabetic patient. This study defines the prevalence of foot pathology, lower extremity complications, and known risk factors for ulceration in a cross-sectional analysis of 92 diabetic patients in a Veterans Affairs Metabolic Clinic. Sixteen percent of patients had a history of lower extremity comp...

Thermography is a useful tool since it provides information that may help in the diagnostic of several diseases in a noninvasive and fast way. Particularly, thermography has been applied in the study of the diabetic foot. However, most of these studies report only qualitative information making it difficult to measure significant parameters such as temperature variations. These variations are i...

Introduction:We evaluated the performance of muscle perfusion scan (MPS) to assess muscle perfusion reserve (MPR) for prediction of incident diabetic foot ulcerations (DFU). Methods: We recruited 41 diabetic patients without any history of DFU. Five mCi 99mTc-MIBI was injected intravenously during repetitive dorsal and plantar right foot flexions. T...

Diabetic foot problems are not very glamorous. Nevertheless, the diabetic foot is the most common complication of diabetes, greater than retinopathy, nephropathy, heart attack and stroke combined. Throughout the world, foot lesions and foot infections are the leading causes of hospitalization and prolonged hospital stays for diabetics. Diabetic foot ulceration is the result of trauma to an inse...

Although neuropathic ulceration remains the commonest type of foot ulcers among patients with diabetes, recent data suggest that ischemic (and therefore, neuroischemic) ulcers are on the rise. The high prevalence and incidence of diabetes and its attendant foot complications, coupled with the current trend where increasingly diabetes care is being provided by general practitioners (primary care...

Diabetes is one of the foremost causes of death in many countries and a leading cause of blindness, renal failure, and non-traumatic amputation. Therefore, diabetic foot ulceration and amputation cause extensive burden on individuals and health care systems in developed and developing countries. Due to the multi-disciplinary requirements for the treatment of diabetic foot ulceration, telemedici...

Previous topical growth factor studies have shown that recombinant human platelet-derived growth factor-BB isomer (rhPDGF-BB) is an efficacious treatment of chronic diabetic foot ulceration. A newer treatment, autologous platelet-rich plasma (PRP), represents a greater similarity to the natural healing process as a composite of multiple growth factors, is safe due to its autologous nature, and ...

It is estimated that approximately 15% of diabetic people world-wide will at some stage develop diabetic foot ulceration. The prevalence of active foot ulceration varies from approx‐ imately 1% in certain European and North American studies to more than 11% in reports from some African countries (table 1). Although there have been many developments in recent years which encourage optimism for f...

BACKGROUND A comprehensive understanding of clinical risk factors for developing foot ulcerations would help clinicians to categorize patients by their risk status and schedule intervention resources accordingly to prevent amputation. OBJECTIVE To evaluate risk factors for foot ulcerations among persons with diabetes mellitus. METHOD We enrolled 225 age-matched patients, 46.7% male, with a ...

The number of people with diabetes worldwide was estimated at 131 million in 2000; it is projected to increase to 366 million by 2030.1 Previous studies have indicated that diabetic patients have up to a 25% lifetime risk of developing a foot ulcer.2 The annual incidence of diabetic foot ulcers is ~ 3%, and the reported incidence in U.S. and U.K. studies ranges as high as 10%.3 Once an ulcer ha...