Diabetes mellitus (DM) is a risk factor for periodontal diseases and oral complications are frequently encountered in diabetic patients. In recent studies it was hypothesed that, the gingival crevicular fluid (GCF) prostoglandin E2 (PGE2) levels are higher in type I diabetic individuals than non diabetics. The aim of our study is to determine the GCF PGE2 levels of the individuals with type II ...

The role of tumor necrosis factor alpha (TNF-alpha) in the pathogenesis of autoimmune diabetes mellitus was tested in the nonobese mouse (NOD) model system. The effects of TNF-alpha were assessed on three levels: (i) insulitis development, (ii) development of overt diabetes, (iii) adoptive transfer of diabetes by splenic lymphocytes. Spontaneous diabetes mellitus was blocked in NOD mice by long...

In this experiment, we established an animal model of gestational diabetes mellitus rats using streptozotocin. Using the rat model of GDM, the pregnant rats in 1-19d were divided into three groups: (1) Zuogui Wan gestational diabetes mellitus group (group I, n = 12), (2) gestational diabetes mellitus rats as the control group (group II, n = 11), and (3) rats of normal pregnancy group (group III...

conclusions in type ii diabetes, the increased susceptibility of ldl to oxidation is related to hyperglycemia and low aop. background type ii diabetes mellitus is a complex heterogeneous group of metabolic conditions characterized by an increased level of blood glucose, due to impairment in insulin action and/or insulin secretion. hyperglycemia is a major factor in the pathogenesis of atheroscl...

An association between diabetes and periodontitis has been long suspected and has now been reasonably well documented for both type I insulin dependent diabetes mellitus and type II non insulin dependent diabetes mellitus. Diabetes mellitus is a systemic complication affecting both the quality and length of life. The interrelationship between periodontitis and diabetes provides an example of sy...

background: correlation between diabetes mellitus (dm) and oral lichen planus (olp) seems probable. since interleukin‑8 (il‑8) is an important inflammatory mediator involved in both conditions, this study aimed to measure and compare the serum level of il‑8 in dm, olp, and dm + olp patients in comparison with healthy individuals. materials and methods: this cross sectional study was conducted o...

Purpose :To assess the association of Diabetic Rtinopathy in Type – II Diabetes Mellitus with HbA1c (Glycosylated Haemoglobin) levels. Materials and Methods :Present study was carried out in type – II Diabetes Mellitus patients at Dr. PSIMS & RF, Chinnaoutpalli. Results : Out of 100 patients in the study the mean age of Diabetes Mellitus is 15.99 years + 5.68 years. The mean of HbA1c is in the ...

Metformin is an antihyperglycemic agent commonly used for the treatment of Type II diabetes mellitus. However, its effects on patients are derived usually from clinical experiments. In this study, a dynamic model of Type II diabetes mellitus with the treatment of metformin is proposed. The Type II diabetic model is a modification of an existing compartmental diabetic model. The dynamic simulati...