Di(2-ethylhexyl) phthalate (DEHP), as a widespread environmental pollutant and an endocrine disruptor, can disturb the homeostasis of thyroid hormones (THs). In order to elucidate roles of the MAPK and PI3K/Akt pathways and hepatic enzymes in thyroid-disrupting effects of DEHP, Sprague-Dawley rats were dosed with DEHP by gavage for 30 consecutive days; Nthy-ori 3-1 cells were treated with DEHP ...

The rough relational database model was developed for the management of uncertainty in relational databases. A particular type of knowledge discovery, attribute oriented induction of rules from generalized data is described in this paper. Rough Relational Databases In rough sets (Pawlak 1984) an approximation space is defined on some universe U by defining some equivalence relation that partiti...

BACKGROUND Phthalates have antiandrogenic effects and may disrupt lipid and carbohydrate metabolism. Racial/ethnic subpopulations have been documented to have varying urinary phthalate concentrations and prevalences of childhood obesity. OBJECTIVE We examined associations between urinary phthalate metabolites and body mass outcomes in a nationally representative sample of U.S. children and ad...

BACKGROUND AND OBJECTIVES One to two per cent of patients in need of red cell transfusion carry irregular antibodies to red blood cell (RBC) antigens and have to be supplied with specially selected blood units. To be able to respond to those requests, blood centres have to screen a significant number of donors for a variety of antigens serologically, which is a costly and through the shortage o...

A recently reported solution for stationary stability of a thermosolutal system with Soret diffusion is re-derived and examined using a symbolic computational package. Symbolic computational languages are well suited for such an analysis and facilitate a pragmatic approach that is adaptable to similar problems. Linearization of the equations, normal mode analysis, and extraction of the final so...

Those who use SAS Proc Lifetest know that it performs the two best known non-parametric tests to compare survival distributions – the Log Rank Test and the Wilcoxon-Gehan Test. In fact, however, these two tests are actually two members of a large class of linear rank tests. These tests are all equally valid, but will have different power. The specific linear rank test having greatest power wil...

Abstract Environmental adaptation of deciduous fruit trees largely depends on their ability to synchronize growth and development with seasonal climate change. Winter dormancy flower buds is a key process prevent frost damage ensure reproductive success. Temperature crucial environmental stimulus influencing the timing flowering, only occurring after fulfillment certain temperature requirements...

Di-(2-ethylhexyl)phthalate (DEHP) was a widely used chemical with human toxicity. Recent in vivo and in vitro studies suggested that DEHP-exposure may be associated with altered serum thyroid hormones (THs) levels, but the underlying molecular mechanisms were largely unknown. To explore the possible molecular mechanisms, 128 Wistar rats were dosed with DEHP by gavage at 0, 150, 300, and 600 mg/...