It was most unfortunate that, because of the minimal risk of producing a tumour at the site of injection, the use of intramuscular iron-dextran complex, used for some time as an effective prophylactic against late anaemia of prematurity, had to be discontinued. A single injection had a long term effect and avoided the need for daily oral iron. Thus it became necessary to determine if oral treat...

Dextran-b-polystyrene diblock copolymers forming miscellaneous spherical self-assemblies in water were obtained by chemical modification of the anomeric extremity of a commercial dextran followed by atom transfer radical polymerisation of styrene.

Studies of the effect of heparin injections on the serum lipoproteins of man and animals are in progress in several laboratories. Gofman and his collaborators have shown that heparin injection results in the larger lipoprotein complexes being converted to smaller ones as shown by the changes in ultra-centrifugal flotation patterns; see, for instance, Graham, Lyon, Gofman, Jones, Yankley, Simont...

Attachment and penetration of influenza virus into clone 1-5C-4 cells were quantitatively determined by the immunofluorescent cell-counting assay. Aided by centrifugal force, more than 95% of virus inocula of five representative influenza virus strains (A(0)/PR8, A(1)/Ann Arbor, A(2)/Japan, B/Lee, B/Great Lakes) were attached to cells at a linear rate within 10 min, in contrast to approximately...

Acetolysis of dextran B-1299-S provides a preparative approach to crystalline u-kojibiose octaacetate. The latter was transformed via crystalline hepta-O-acetylct-kojibiosyl bromide into p-nitrophenyl and p-isothiocyanatophenyl /3-kojibiosides.

A sensitive, quantitative and reproducible plaque assay for the measurement of the simian rotavirus SAII is described. Plaque formation required the presence of the facilitators pancreatin or trypsin and diethylaminoethyl-dextran in the agar overlay. SAII produced plaques in three continuous primate cell lines: MA-104, CV-1 and LLC-MK2. MA-104 cells were the most sensitive.

The effects of all-trans retinoic acid (RA) on the differentiation of the reticulospinal system were studied in Xenopus. RA was applied in concentrations of 10(-5) and 10(-6) M for 30 min at stage 12. When siblings had reached stages 46-48, the spinal cord was transected in anesthetized control and experimental animals and the reticulospinal cells were visualized through retrograde transport of...

TPDex, a putative dextranase from Thermoanaerobacter pseudethanolicus, was purified as a single 70 kDa band of 7.37 U/mg. Its optimum pH was 5.2 and the enzyme was stable between pH 3.1 and 8.5 at 70 degrees C. A half-life comparison showed that TPDex was stable for 7.4 h at 70 degrees C, whereas Chaetominum dextranase (CEDex), currently used as a dextranase for sugar milling, was stable at 55 ...