In this paper, we apply continuous review (S-1, S) policy for inventory control in a three-echelon supply chain (SC) including r identical retailers, a central warehouse with limited storage space, and two independent manufacturing plants which offer two kinds of product to the customer. The warehouse of the model follows (M/M/1) queue model where customer demands follow a Poisson probabilit...

background a model of quality management called strategic collaborative quality management (scqm) model was developed based on the quality management literature review, the findings of a survey on quality management assessment in healthcare organisations, semi-structured interviews with healthcare stakeholders, and a delphi study on healthcare quality management experts. the purpose of this stu...

foundations behavior is affected by soil behavior which can vary from dilative to contractive depending on the stress level, particularly in dense frictional soils. the zero extension lines (zel) method has been generally developed to predict the foundations behavior. knowledge of soil behavior enables the zel method to predict the general and local shear failure modes. in this paper, a relativ...

One of the newest of viscoelastic RANS turbulence models for drag reducing channel flow with polymer additives is studied in different flow and rheological properties. In this model, finitely extensible nonlinear elastic-Peterlin (FENE-P) constitutive model is used to describe the viscoelastic effect of polymer solution and turbulence model is developed in the k-ϵ-(ν^2 ) ̅-f framework. The geome...

A numerical model is developed in this study with various components for simulating the complex flow phenomena in urban drainage basins. The model integrates the HEC-1 model, a 1-D dynamic channel-flow model, a 2-D non-inertia overland-flow model and the SWMM model to reflect the hydraulic processes in areas with different characteristics. The inundation of underground infrastructure during flo...

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Pharmacokinetic-pharmacodynamic (PK-PD) modeling has emerged as a major tool in clinical pharmacology to optimize drug use by designing rational dosage forms and dosage regimes. Quantitative representation of the dose-concentration-response relationship should provide information for the prediction of the level of response to a certain level of drug dose. This paper describes the experimental d...