Methods We realized a 2 years ambispective study for assessment safety and efficacy of subcutaneous immunotherapy with a dust mite vaccine with the adjuvant L-tyrosine. We reviewed the data of 292 patients with allergic rhinitis and/or asthma. They are sensitized to Dermatophagoides pteronyssinus or Dermatophagoides farinae and or Blomia tropicallis. A data base was constructed to allow complet...

AIM Determination of prevalence of sensitization to Dermatophagoides pteronyssinus, Dermatophagoides farinae (pyroglyphid mites), Lepidoglyphus destructor, and Tyrophagus putrescentiae (non-pyroglyphid mites) in urban continental Croatia. METHODS Specific IgE (sIgE) and skin prick test (SPT) for D. pteronyssinus, D. farinae, L. destructor, and T. putrescentiae were performed in 67 men. SPT wa...

RESULTS: Fifty patients (68.5%) had positive skin test responses. There were positive responses to D. pteronyssinus (52.0%), B. tropicalis (53.4%), T. putrescentiae (15.0%), E. maynei (12.3%), L. destructor (8.2%), B. germanica (20.5%), P. americana (21.9%), Felis catus (10.9%), C. herbarium (2.7%), A. alternata (4.1%), and P. notatun (1.3%). The exposure to mite and cockroach allergens was sim...

Background House Dust Mites are important etiological agents of respiratory allergy. Allergen mixtures are often used for specific immunotherapy in polysensitized patients, although scientific evidence to support its efficacy, safety and stability is scarce. Sublingual immunotherapy (SLIT) is being gradually accepted as an alternative to conventional subcutaneous immunotherapy. For SLIT, higher...

Twenty-five patients with perennial rhinitis and a positive skin prick test (SPT) for Dermatophagoides pteronyssinus (Dp) and Dermatophagoides farinae (Df) were submitted to nasal provocation and the radioimmunosorbent test (RAST) for specific IgE-antibodies. We found a significant correlation in the reaction to both allergen extracts for all parameters examined. In addition, there was a signif...

OBJECTIVE To evaluate hypersensitivity to Dermatophagoides pteronyssinus (D. pteronyssinus) and Dermatophagoides farinae (D. farinae) in pediatric patients with asthma, and the use of acaricides. METHODS This is a randomized controlled trial in 82 asthmatic children. They were recruited and evaluated for severity and chronicity according to the Global Initiative for Asthma Guidelines. The s...

CONTEXT AND OBJECTIVE Knowledge of the profile of allergen sensitization among children is important for planning preventive measures. The objective of this study was to assess the prevalence and profile of sensitization to inhaled allergens and food among children and adolescents in an outpatient population in the city of Palmas. DESIGN AND SETTING Cross-sectional study at outpatient clinics...

Background The house dust mites are cosmopolitan guest in human habitation. Dust mites occur in nearly all homes. They are generally found in pillows, bed sheets, mattress, stuff toys, carpets etc. Dust mites feed on organic detritus such as flakes of shed human skin and flourish in stable environment of dwellings. Exposure to house dust mites is recognized as major cause allergy worldwide. The...

Methods Our prospective study included eighty-eight asthmatic children, with ages between 1 and 18 years, who were admitted to the Clinic of Pediatrics I from Târgu Mureş, Romania, between October 2008 and June 2010. We analyzed the age, month of birth, sensitization to a given antigen (Dermatophagoides pteronyssinus, Dermatophagoides farinae, milk proteins, egg, mold, dog epithelium, cat epith...