The high computational cost of SPH remains problematic in dealing with wave propagation, especially when the domains considered are large. In order to overcome this difficulty, we propose to couple 2-D SPH with a 1-D Finite Difference Boussinesq-type model. The latter deals with wave propagations for most of the spatial domain, whereas SPH computations focus on the shoreline or close to off-sho...

Cardiac tissue is a syncytium of coupled cells with pronounced intrinsic discrete nature. Previous models of cardiac electromechanics often ignore such discrete properties and treat cardiac tissue as a continuous medium, which has fundamental limitations. In the present study, we introduce a 2D electromechanical model for human atrial tissue based on the discrete element method (DEM). In the mo...

Aiming at the impact failure of debris flow grille dam, considering interaction boulder-debris slurry- dam based on SPH-FEM, this article analyzed variation laws velocity, force and support reaction before after slurry boulders passing through dam. The results show that: SPH-FEM coupling method can truly reappear dam; velocity boulder are reduced by nearly 60% effect is remarkable; have seconda...

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Because sphingosine (Sph) is actively incorporated into platelets and rapidly converted to sphingosine 1-phosphate (Sph-1-P), which is then released extracellularly, it is important to study the effects of Sph and Sph-1-P on endothelial cells from the viewpoint of platelet-endothelial cell interaction. In this study, we found that Sph, as well as ceramide, induces apoptosis in human umbilical v...

Sphingosine 1-phosphate (Sph-1-P) has been implicated as an intracellular second messenger in many studies. We investigated the metabolism of Sph-1-P and the mechanism by which Sph-1-P induces activation in enucleated and highly differentiated platelets. Platelets lack Sph-1-P lyase activity, possess persistently active sphingosine (Sph) kinase, and abundantly store Sph-1-P. Although exogenous ...

We present a two-way coupling technique for simulating the complex interaction between hair and fluids. In our approach, the motion of hair and fluids is simulated by evaluating the hydrodynamic forces among them based on boundary handling techniques used in SPH (Smoothed Particle Hydrodynamics) fluids. When hair makes contact with fluids, water absorption inside the hair volume can be simulate...