نتایج جستجو برای: dehydroepiandrosterone sulfate

تعداد نتایج: 60776  

Journal: :The Journal of clinical endocrinology and metabolism 2002
John E Nestler John B Whitfield Terre Y Williams Gu Zhu Juliann Condon Katherine M Kirk Andrew C Heath Grant W Montgomery Nicholas G Martin

Previous studies have shown a significant effect of insulin administration on serum dehydroepiandrosterone sulfate (DHEA-S) concentration and its metabolic rate, with evidence for the effect in men, but not in women. This could lead to differences in the sources of variation in serum DHEA-S between men and women and in its covariation with insulin concentration. This study aimed to test whether...

Journal: :Respiratory Research 2006
Edouard H Debonneuil Janine Quillard Etienne-Emile Baulieu

BACKGROUND Survival remains an issue in pulmonary hypertension, a chronic disorder that often affects aged human adults. In young adult mice and rats, chronic 50% hypoxia (11% FIO2 or 0.5 atm) induces pulmonary hypertension without threatening life. In this framework, oral dehydroepiandrosterone was recently shown to prevent and reverse pulmonary hypertension in rats within a few weeks. To eval...

2015
Anna-Karin Lennartsson Töres Theorell Mark M. Kushnir Ingibjörg H. Jonsdottir Onno C Meijer

OBJECTIVE Dehydroepiandrosterone sulphate (DHEA-s) is an anabolic protective hormone of importance for maintenance of health. DHEA-s levels peak in young adults and decline thereafter with age. DHEA-s has previously been shown to be lower in individuals reporting prolonged stress. This study investigates DHEA-s levels in patients with clinical burnout, a disorder caused by long-term psychosocia...

Journal: :JAMA 2005
Susan R Davis Sonia L Davison Susan Donath Robin J Bell

CONTEXT It has been proposed that low sexual desire and sexual dysfunction are associated with low blood testosterone levels in women. However, evidence to support this is lacking. OBJECTIVE To determine whether women with low self-reported sexual desire and sexual satisfaction are more likely to have low serum androgen levels than women without self-reported low sexual desire and sexual sati...

Journal: :Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007
Heather Greenlee Charlotte Atkinson Frank Z Stanczyk Johanna W Lampe

Naturopathic physicians commonly make dietary and/or dietary supplement recommendations for breast cancer prevention. This placebo-controlled, parallel-arm, pilot study tested the effects of two naturopathic interventions over five menstrual cycles on sex steroid hormones and metabolic markers in 40 healthy premenopausal women. The intervention arms were as follows: combination botanical supple...

Journal: :Menopause 2006
Robin J Bell Susan Donath Sonia L Davison Susan R Davis

OBJECTIVE We investigated whether there is a relationship between androgens levels and well-being in pre- and postmenopausal women. DESIGN We randomly recruited 1423 women aged 18 to 75 years from the community via the electoral roll. Each provided a morning blood sample and completed the Psychological General Well Being Index questionnaire on the same day. Women were excluded if they took me...

Journal: :Revista brasileira de psiquiatria 2007
Adriana Dias Elpo Barbosa Gina Struffaldi Morato

OBJECTIVE The objective of the present study was to investigate the effect of epipregnanolone on the influence of neurosteroids on the development of rapid tolerance to the motor impairing and hypothermic effects of ethanol. METHOD Experiment 1: on Day 1 groups of mice were pretreated with saline or with epipregnanolone. After 30 min each group was further divided in subgroups that received e...

Journal: :Physiological research 2012
A Garrido Y Munoz W Sierralta L Valladares

The aim of the present research was to study the uptake of DHEAS, and to establish the intracrine capacity of human platelets to produce sex steroid hormones. The DHEAS transport was evaluated through the uptake of [(3)H]-DHEAS in the presence or absence of different substrates through the organic anion transporting polypeptide (OATP) family. The activity of sulfatase enzyme was evaluated, and ...

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